Modelling wall shear stress in small arteries using method: influence of the endothelial wall profile

被引：9

作者：

Pontrelli, Giuseppe ^{[1
]}

Koenig, Carola S. ^{[2
]}

Halliday, Ian ^{[3
]}

Spencer, Timothy J. ^{[3
]}

Collins, Michael W. ^{[4
]}

Long, Quan ^{[2
,4
]}

Succi, Sauro ^{[1
]}

机构：

[1] Natl Res Council IAC CNR, Inst Appl Comp, Rome, Italy

[2] Brunel Univ, Inst Bioengn, London, England

[3] Sheffield Hallam Univ, Mat & Engn Res Inst, Sheffield S1 1WB, S Yorkshire, England

[4] Brunel Univ, Sch Engn & Design, London, England

来源：

MEDICAL ENGINEERING & PHYSICS | 2011年 / 33卷 / 07期

基金：

英国生物技术与生命科学研究理事会;

关键词：

Arterial endothelium; Blood flow; Wall shear stress; Lattice Boltzmann methods LBM; LATTICE BOLTZMANN-EQUATION; BLOOD-FLOW; FLUID; CHANNELS; FORCES; CODE;

D O I：

10.1016/j.medengphy.2011.03.009

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In order to address the problem of blood flow over the endothelium in small arteries, the near-endothelial region is here studied in more detail. The method used is a finite-volume discretisation of a Lattice Boltzmann equation over unstructured grids, named unstructured lattice Boltzmann equation (ULBE). It is a new scheme based on the idea of placing the unknown fields at the nodes of the mesh and evolving them based on the fluxes crossing the surfaces of the corresponding control volumes. The study shows a significant variation and a high sensitivity of wall shear stress to the height of the endothelium corrugation and the presence of erythrocytes. The latter were modelled as deformable, viscous particles within a fluid continuum. (C) 2011 IPEM. Published by Elsevier Ltd. All rights reserved.

引用

页码：832 / 839

页数：8

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