Cross-species microRNA transmission modulates flavivirus growth in mosquitoes

被引:1
|
作者
Shivaprasad, Shwetha [1 ]
Sarnow, Peter [1 ]
机构
[1] Stanford Univ, Dept Microbiol & Immunol, SOM, Stanford, CA 94305 USA
关键词
RNA;
D O I
10.1016/j.pt.2022.02.007
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Mosquitoes can be infected with a variety of RNA viruses. Recently, Zhu et al. demonstrated that human microRNA hsa-miR-150-5p is acquired by mosquitoes during blood meals and protects the Dengue virus by downregulation of chymotrypsin AaCT-1 mRNA. This finding suggests the use of microRNA antagomirs as an antiviral approach in mosquitoes.
引用
收藏
页码:349 / 350
页数:2
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