Cross-species microRNA transmission modulates flavivirus growth in mosquitoes

被引：1
|
作者：
Shivaprasad, Shwetha [1 ]
Sarnow, Peter [1 ]
机构：
[1] Stanford Univ, Dept Microbiol & Immunol, SOM, Stanford, CA 94305 USA
来源：
TRENDS IN PARASITOLOGY | 2022年 / 38卷 / 05期
关键词：
RNA;
D O I：
10.1016/j.pt.2022.02.007
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Mosquitoes can be infected with a variety of RNA viruses. Recently, Zhu et al. demonstrated that human microRNA hsa-miR-150-5p is acquired by mosquitoes during blood meals and protects the Dengue virus by downregulation of chymotrypsin AaCT-1 mRNA. This finding suggests the use of microRNA antagomirs as an antiviral approach in mosquitoes.
引用
收藏
页码：349 / 350
页数：2
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