Two new chemical constituents from Daphne odora Thunb. var. marginata

被引：30
|
作者：
Zhang, W. [1 ]
Zhang, W. D. [1 ]
Liu, R. H.
Shen, Y. H.
Zhang, C.
Cheng, H. S.
Fu, P.
Shan, L.
机构：
[1] Second Mil Med Univ, Coll Pharm, Shanghai, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200030, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2006年 / 20卷 / 14期
关键词：
Daphne odora thunb. var. marginata; Thymelaeaceae; daphnenone; daphneone; MTT assay; cytotoxic activity;
D O I：
10.1080/14786410601101860
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new phenolic constituents, daphnenone (1) and daphneone (2), were isolated from the stem bark of Daphne odora Thunb. var. marginata. Their structures were established on the basis of spectroscopic analysis. Compounds 1 and 2 were tested for cytotoxic activity by MTT assays on five human tumour cell lines, K562, A549, MCF-7, LOVO and HepG2. Compound 1 showed obvious cytotoxic activity against all the five cell lines.
引用
收藏
页码：1290 / 1294
页数：5
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