Two new chemical constituents from Daphne odora Thunb. var. marginata

被引：30
|
作者：
Zhang, W. [1 ]
Zhang, W. D. [1 ]
Liu, R. H.
Shen, Y. H.
Zhang, C.
Cheng, H. S.
Fu, P.
Shan, L.
机构：
[1] Second Mil Med Univ, Coll Pharm, Shanghai, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200030, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2006年 / 20卷 / 14期
关键词：
Daphne odora thunb. var. marginata; Thymelaeaceae; daphnenone; daphneone; MTT assay; cytotoxic activity;
D O I：
10.1080/14786410601101860
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new phenolic constituents, daphnenone (1) and daphneone (2), were isolated from the stem bark of Daphne odora Thunb. var. marginata. Their structures were established on the basis of spectroscopic analysis. Compounds 1 and 2 were tested for cytotoxic activity by MTT assays on five human tumour cell lines, K562, A549, MCF-7, LOVO and HepG2. Compound 1 showed obvious cytotoxic activity against all the five cell lines.
引用
收藏
页码：1290 / 1294
页数：5
相关论文
共 50 条
  • [21] A new lignan glucoside from the stems of Callicarpa japonica Thunb. var. luxurians Rehd.
    Masateru Ono
    Kenji Mishima
    Toru Yamasaki
    Chikako Masuoka
    Masafumi Okawa
    Junei Kinjo
    Tsuyoshi Ikeda
    Toshihiro Nohara
    Journal of Natural Medicines, 2009, 63 : 86 - 90
  • [22] A new phenylethanoid glycoside from the fruits of Callicarpa japonica Thunb. var. luxurians Rehd.
    Yamasaki, Torn
    Masuoka, Chikako
    Nohara, Toshihiro
    Ono, Masateru
    JOURNAL OF NATURAL MEDICINES, 2007, 61 (03) : 318 - 322
  • [23] Fatty Acid Synthase Inhibitors from Geum japonicum THUNB. var. chinense
    Liu, Hongwei
    Li, Jiankuan
    Zhao, Wenhua
    Bao, Li
    Song, Xiaohong
    Xia, Ying
    Wang, Xue
    Zhang, Chao
    Wang, Xiaozhu
    Yao, Xinsheng
    Li, Ming
    CHEMISTRY & BIODIVERSITY, 2009, 6 (03) : 402 - 410
  • [24] Chemical constituents of Mallotus japonicus Thunb. and their chemotaxonomic significance
    Yuan, Tao
    Hwang, In Hyun
    Na, Minkyun
    BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2024, 113
  • [25] Study on the chemical constituents ofEuonymus alatus (Thunb.) Sleb
    He Lan
    Lu Shu-ming
    Pan Yuan-jiang
    Chen Yao-zu
    Journal of Zhejiang University-SCIENCE A, 2000, 1 (2): : 188 - 189
  • [26] A new diterpenoid and a new triterpenoid glucosyl ester from the leaves of Callicarpa japonica Thunb. var. luxurians Rehd.
    Masateru Ono
    Tomoyo Chikuba
    Kenji Mishima
    Toru Yamasaki
    Tsuyoshi Ikeda
    Hitoshi Yoshimitsu
    Toshihiro Nohara
    Journal of Natural Medicines, 2009, 63 : 318 - 322
  • [27] A new diterpenoid and a new triterpenoid glucosyl ester from the leaves of Callicarpa japonica Thunb. var. luxurians Rehd.
    Ono, Masateru
    Chikuba, Tomoyo
    Mishima, Kenji
    Yamasaki, Toru
    Ikeda, Tsuyoshi
    Yoshimitsu, Hitoshi
    Nohara, Toshihiro
    JOURNAL OF NATURAL MEDICINES, 2009, 63 (03) : 318 - 322
  • [28] Synthesis of vinyl caffeate, an antioxidant from Perilla frutescens Britton var. crispa (Thunb.)
    Kavitha, J
    Rajasekhar, D
    Subbaraju, GV
    Ramesh, GN
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1999, 38 (11): : 1280 - 1281
  • [29] Salt Tolerance Assessment with NaCl of Stauntonia hexaphylla (Thunb.) Decene. and Raphiolepis indica var. umbellata (Thunb.) Ohashi
    Min, Su
    Shin, Hyeon Cheol
    Kim, Inhea
    Huh, Keun Young
    Kim, Daeil
    KOREAN JOURNAL OF HORTICULTURAL SCIENCE & TECHNOLOGY, 2013, 31 (05) : 617 - 625
  • [30] FLAVONOIDS DISTRIBUTION IN PAULOWNIA TOMENTOSA (THUNB.) STEUD. VAR. TOMENTOSA
    Si, Chuan-Ling
    Lu, Yi-Yuan
    Wang, Lijun
    Liu, Peng-Tao
    Yoon, Byung-Ho
    Bae, Young-Soo
    16TH INTERNATIONAL SYMPOSIUM ON WOOD, FIBER AND PULPING CHEMISTRY, PROCEEDINGS, VOLS I & II, 2011, : 120 - 123
12345