Inhibitory effects of bovine lactoferrin and lactoferricin B on Enterobacter sakazakii

被引:20
|
作者
Wakabayashi, Hiroyuki [1 ]
Yamauchi, Koji [1 ]
Takase, Mitsunori [2 ]
机构
[1] Inst Food Sci & Technol, Kanagawa 2288583, Japan
[2] Morinaga Milk Ind Co Ltd, Nutr Sci Inst, Kanagawa 2288583, Japan
关键词
Enterobacter sakazakii; lactoferrin; lactoferricin; antimicrobial activity; infant formula;
D O I
10.4265/bio.13.29
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The susceptibility of Enterobacter sakazakii, a food-borne pathogen, to several metal-bound forms of bovine lactoferrin (LF), pepsin-hydrolyzed LF (LF-hyd), and LF-derived peptide lactoferricin B (LFcin B) was tested. MIC and MBC testing revealed that 4 strains of E sakazakii show susceptibility to apo- and Cu-LF, LF-hyd, and LFcin B, but not to Fe-LF, similarly to Escherichia coli. A growth curve test indicated that E sakazakii was inhibited in a dose-dependent manner by apo-LF at 0.5 to 8 mg/ml. Even after being heated at 80 degrees c, LF at above 1 mg/ml inhibited the bacterial growth. These results suggest that bovine LF-related compounds may be useful for the inhibition of E. sakazakii in foods.
引用
收藏
页码:29 / 32
页数:4
相关论文
共 50 条
  • [31] Molecular mechanism of inhibitory effects of bovine lactoferrin on the growth of oral squamous cell carcinoma
    Chea, Chanbora
    Miyauchi, Mutsumi
    Inubushi, Toshihiro
    Ayuningtyas, Nurina Febriyanti
    Subarnbhesaj, Ajiravudh
    Phuong Thao Nguyen
    Shrestha, Madhu
    Haing, Sivmeng
    Ohta, Kouji
    Takata, Takashi
    PLOS ONE, 2018, 13 (01):
  • [32] Molecular Mechanisms of Inhibitory Effects of Bovine Lactoferrin on Invasion of Oral Squamous Cell Carcinoma
    Chea, Chanbora
    Miyauchi, Mutsumi
    Inubushi, Toshihiro
    Okamoto, Kana
    Haing, Sivmeng
    Takata, Takashi
    PHARMACEUTICS, 2023, 15 (02)
  • [33] Bovine lactoferrin and lactoferricin on plasma-deposited coating against spoilage Pseudomonas spp.
    Quintieri, L.
    Pistillo, B. R.
    Caputo, L.
    Favia, P.
    Baruzzi, F.
    INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES, 2013, 20 : 215 - 222
  • [34] Bovine Lactoferrampin, Human Lactoferricin, and Lactoferrin 1-11 Inhibit Nuclear Translocation of HIV Integrase
    Winston Yan Wang
    Jack Ho Wong
    Denis Tsz Ming Ip
    David Chi Cheong Wan
    Randy Chifai Cheung
    Tzi Bun Ng
    Applied Biochemistry and Biotechnology, 2016, 179 : 1202 - 1212
  • [35] Novel Identification of Group B Streptococcus and Enterobacter sakazakii in Infant Suspected to Septicemia
    Modaresi, Farzan
    Hasannezhad, Arash
    Rezaei, Zahra
    Kazemi, Akbar
    AMBIENT SCIENCE, 2019, 6H (01) : 24 - 27
  • [36] Bovine Lactoferrampin, Human Lactoferricin, and Lactoferrin 1-11 Inhibit Nuclear Translocation of HIV Integrase
    Wang, Winston Yan
    Wong, Jack Ho
    Ip, Denis Tsz Ming
    Wan, David Chi Cheong
    Cheung, Randy Chifai
    Ng, Tzi Bun
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2016, 179 (07) : 1202 - 1212
  • [37] Inhibitory Effects of Synthetic Peptides Containing Bovine Lactoferrin C lobe Sequence on Bacterial Growth
    Kim, Woan-Sub
    Ohashi, Midori
    Shimazaki, Kei-ichi
    KOREAN JOURNAL FOR FOOD SCIENCE OF ANIMAL RESOURCES, 2016, 36 (04) : 452 - 457
  • [38] KILLING OF CANDIDA-ALBICANS BY LACTOFERRICIN-B, A POTENT ANTIMICROBIAL PEPTIDE DERIVED FROM THE N-TERMINAL REGION OF BOVINE LACTOFERRIN
    BELLAMY, W
    WAKABAYASHI, H
    TAKASE, M
    KAWASE, K
    SHIMAMURA, S
    TOMITA, M
    MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 1993, 182 (02) : 97 - 105
  • [39] Inhibitory Effect of Bovine Lactoferrin on Catechol-O-Methyltransferase
    Ikeda, Masayuki
    Iijima, Hiroshi
    Shinoda, Ichizo
    Iwamoto, Hiroshi
    Takeda, Yasuhiro
    MOLECULES, 2017, 22 (08)
  • [40] Effects of lactoferrin and lactoferricin(R) on the release of interleukin 8 from human polymorphonuclear leukocytes
    Shinoda, I
    Takase, M
    Fukuwatari, Y
    Shimamura, S
    Koller, M
    Konig, W
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1996, 60 (03) : 521 - 523