Prevention of Akt phosphorylation is a key to targeting pancreatic cancer stem-like cells by mTORC1 inhibition.

被引：0
|
作者：
Matsubara, Shyuichiro [1 ]
Shimono, Ryuichi [2 ]
Furukawa, Tatsuhiko [3 ]
Takao, Sonshin [1 ]
机构：
[1] Kagoshima Univ, Sch Med, Canc & Regenerat Med, Kagoshima, Japan
[2] Kagawa Univ, Dept Pediat Surg, Takamatsu, Kagawa, Japan
[3] Kagoshima Univ, Sch Med, Mol Oncol, Kagoshima, Japan
来源：
CANCER SCIENCE | 2021年 / 112卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
OJ11-1-6
引用
收藏
页码：378 / 378
页数：1
相关论文
共 50 条
  • [31] Metabolic enzymes: key modulators of functionality in cancer stem-like cells
    Dong, Bo-Wen
    Qin, Guang-Ming
    Luo, Yan
    Mao, Jian-Shan
    ONCOTARGET, 2017, 8 (08) : 14251 - 14267
  • [32] Epithelial to mesenchymal transition and the generation of stem-like cells in pancreatic cancer
    Rhim, Andrew D.
    PANCREATOLOGY, 2013, 13 (02) : 114 - 117
  • [33] Secretome protein signature of human pancreatic cancer stem-like cells
    Brandi, Jessica
    Dalla Pozza, Elisa
    Dando, Ilaria
    Biondani, Giulia
    Robotti, Elisa
    Jenkins, Rosalind
    Elliott, Victoria
    Park, Kevin
    Marengo, Emilio
    Costello, Eithne
    Scarpa, Aldo
    Palmieri, Marta
    Cecconi, Daniela
    JOURNAL OF PROTEOMICS, 2016, 136 : 1 - 12
  • [34] Targeting ovarian cancer stem cell by Dot1L inhibition.
    Zhang, Yaqi
    Wang, Yinu
    Zhao, Guangyuan
    Matei, Daniela
    CLINICAL CANCER RESEARCH, 2020, 26 (13) : 79 - 79
  • [35] Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells
    Thedieck, Kathrin
    Holzwarth, Birgit
    Prentzell, Mirja Tamara
    Boehlke, Christopher
    Klaesener, Kathrin
    Ruf, Stefanie
    Sonntag, Annika Gwendolin
    Maerz, Lars
    Grellscheid, Sushma-Nagaraja
    Kremmer, Elisabeth
    Nitschke, Roland
    Kuehn, E. Wolfgang
    Jonker, Johan W.
    Groen, Albert K.
    Reth, Michael
    Hall, Michael N.
    Baumeister, Ralf
    CELL, 2013, 154 (04) : 859 - 874
  • [36] Targeting metastasis and cancer stem-like cells in triple negative breast cancer through inhibition of focal adhesion kinase
    Jones, Samuel
    Smith, Christopher
    Hiscox, Stephen
    Jiang, Wen G.
    CANCER RESEARCH, 2016, 76
  • [37] AXL inhibition in ovarian cancer stem-like cells increases chemosensitivity
    Kim, Jin-Young
    Chung, Hyewon
    Shin, So-Jin
    Ha, Eunyoung
    Cho, Chi-Heum
    CANCER RESEARCH, 2017, 77
  • [38] Inhibition of phosphodiesterase 4D suppresses mTORC1 signaling and pancreatic cancer growth
    Jeong, Mi-Hyeon
    Urquhart, Greg
    Lewis, Cheryl
    Chi, Zhikai
    Jewell, Jenna L.
    JCI INSIGHT, 2023, 8 (13)
  • [39] Targeting cancer stem-like cells in glioblastoma and colorectal cancer through metabolic pathways
    Kahlert, U. D.
    Mooney, S. M.
    Natsumeda, M.
    Steiger, H. -J.
    Maciaczyk, J.
    INTERNATIONAL JOURNAL OF CANCER, 2017, 140 (01) : 10 - 22
  • [40] The Low Chamber Pancreatic Cancer Cells Had Stem-Like Characteristics in Modified Transwell System: Is It a Novel Method to Identify and Enrich Cancer Stem-Like Cells?
    Wang, Dongqing
    Zhu, Haitao
    Liu, Yanfang
    Liu, Qing
    Xie, Xiaodong
    Zhou, Yuepeng
    Zhang, Lirong
    Zhu, Yan
    Zhang, Zhijian
    Su, Zhaoliang
    BIOMED RESEARCH INTERNATIONAL, 2014, 2014
12345