Validation of a Monte Carlo simulation of the Inveon PET scanner using GATE

被引：8
|
作者：
Lu, Lijun
Zhang, Houjin
Bian, Zhaoying
Ma, Jianhua [1 ]
Feng, Qiangjin
Chen, Wufan [1 ]
机构：
[1] Southern Med Univ, Sch Biomed Engn, Guangzhou 510515, Guangdong, Peoples R China
来源：
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2016年 / 828卷
基金：
中国国家自然科学基金;
关键词：
PET; PET simulation; Inveon scanner; GATE; SPECT; PLATFORM; MODEL;
D O I：
10.1016/j.nima.2016.04.059
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
The purpose of this study is to validate the application of GATE (Geant4 Application for Tomographic Emission) Monte Carlo simulation toolkit in order to model the performance characteristics of Siemens Inveon small animal PET system. The simulation results were validated against experimental/published data in accordance with the NEMA NU-4 2008 protocol for standardized evaluation of spatial resolution, sensitivity, scatter fraction (SF) and noise equivalent counting rate (NECR) of a preclinical PET system. An agreement of less than 18% was obtained between the radial, tangential and axial spatial resolutions of the simulated and experimental results. The simulated peak NECR of mouse-size phantom agreed with the experimental result, while for the rat-size phantom simulated value was higher than experimental result. The simulated and experimental SFs of mouse- and rat-size phantom both reached an agreement of less than 2%. It has been shown the feasibility of our GATE model to accurately simulate, within certain limits, all major performance characteristics of Inveon PET system. (C) 2016 Published by Elsevier B.V.
引用
收藏
页码：170 / 175
页数：6
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