Catalytic enantioselective thioester aldol reactions that are compatible with protic functional groups

被引：151
|
作者：
Magdziak, D [1 ]
Lalic, G [1 ]
Lee, HM [1 ]
Fortner, KC [1 ]
Aloise, AD [1 ]
Shair, MD [1 ]
机构：
[1] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 20期
关键词：
D O I：
10.1021/ja051759j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This communication reports highly enantioselective and diastereoselective methyl malonic acid half thioester (MeMAHT) aldol reactions that are compatible with protic functional groups and enolizable aldehydes, affording syn S-phenyl thiopropionates. Copyright © 2005 American Chemical Society.
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页码：7284 / 7285
页数：2
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