Matched-pair analysis of survival in the patients with T3 laryngeal squamous cell carcinoma treated with supracricoid partial laryngectomy or total laryngectomy

被引：8
|
作者：
Xial, Xin [1 ,2 ]
Zhu, Ying-Ying [1 ,2 ]
Diao, Wen-Wen [1 ,2 ]
Zhu, Xiao-Li [1 ,2 ]
Shi, Xiao-Hua [2 ,3 ]
Li, Wu-Yi [1 ,2 ]
Gao, Zhi-Qiang [1 ,2 ]
Li, Guo-Jun [1 ,2 ]
Chen, Xing-Ming [1 ,2 ]
机构：
[1] Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Otolaryngol Head & Neck Surg, 1 Shuaifuyuan, Beijing 100730, Peoples R China
[2] Chinese Acad Med Sci, 1 Shuaifuyuan, Beijing 100730, Peoples R China
[3] Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Pathol, Beijing, Peoples R China
来源：
ONCOTARGETS AND THERAPY | 2018年 / 11卷
关键词：
survival analysis; matched-pair analysis; laryngeal neoplasms; laryngectomy; squamous cell carcinoma; CRICOHYOIDOPEXY; CANCER; CRICOHYOIDOEPIGLOTTOPEXY; PRESERVATION; OUTCOMES; T3-T4;
D O I：
10.2147/OTT.S175358
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Background: The survival outcomes between supracricoid partial laryngectomy (SCPL) and total laryngectomy (TL) were compared in the groups of matched-pair patients with T3 laryngeal squamous cell carcinoma (LSCC). Methods: Patients with T3 LSCC were matched based on prognostic factors. The Kaplan-Meier curve and the Cox proportional hazards model were used for analysis on survival. Results: A total of 212 patients with T3 LSCC were included after matching (106 underwent SCPL and 106 underwent TL). Multivariable analysis showed no differences in overall survival (hazard risk [HR]=1.15; 95% CI: 0.79-1.67; P=0.47), disease-specific survival (HR=1.11; 95% CI: 0.69-1.80; P=0.66), and recurrence-free survival (HR=1.07; 95% CI: 0.68-1.68; P=0.77) between the SCPL group and TL group. Conclusion: SCPL provides reliable therapeutic outcomes and can be used to avoid a TL surgery in sonic patients with advanced primary laryngeal cancer.
引用
收藏
页码：7947 / 7953
页数：7
相关论文
共 50 条
  • [41] Survival Outcomes in T3 Laryngeal Cancers: Primary Total Laryngectomy vs. Concurrent Chemoradiation or Radiation Therapy-A Meta-Analysis
    Rao, Karthik Nagaraja
    Pai, Prathamesh S.
    Dange, Prajwal
    Kowalski, Luiz P.
    Strojan, Primoz
    Makitie, Antti A.
    Guntinas-Lichius, Orlando
    Robbins, K. Thomas
    Rodrigo, Juan P.
    Eisbruch, Avraham
    Takes, Robert P.
    de Bree, Remco
    Coca-Pelaz, Andres
    Piazza, Cesare
    Chiesa-Estomba, Carlos
    Lopez, Fernando
    Saba, Nabil F.
    Rinaldo, Alessandra
    Ferlito, Alfio
    BIOMEDICINES, 2023, 11 (08)
  • [42] Primary Total Laryngectomy versus Organ Preservation for Locally Advanced T3/T4a Laryngeal Cancer
    Lee, Maxwell Y.
    Belfiglio, Mario
    Zeng, Johnathan
    Fleming, Christopher W.
    Koyfman, Shlomo
    Joshi, Nikhil P.
    Lamarre, Eric
    Prendes, Brandon
    Scharpf, Joseph
    Lorenz, Robert R.
    Woody, Neil M.
    Adelstein, David J.
    Geiger, Jessica L.
    Chute, Deborah J.
    Ku, Jamie A.
    LARYNGOSCOPE, 2023, 133 (05): : 1122 - 1131
  • [43] Survival Analysis of Elderly Patients With Laryngeal Cancer After Total Laryngectomy: A Retrospective Cohort Study
    Avdulla, Christos S.
    Mastronikolis, Nicholas S.
    Tachirai, Ntaniela
    Leotsinidis, Michalis
    Jelastopulu, Eleni
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2024, 16 (05)
  • [44] Laryngeal Compartmentalization Does Not Affect the Prognosis of T3-T4 Laryngeal Cancer Treated by Upfront Total Laryngectomy
    Marchi, Filippo
    Missale, Francesco
    Sampieri, Claudio
    Filauro, Marta
    Iandelli, Andrea
    Parrinello, Giampiero
    Incandela, Fabiola
    Smeele, Ludwig E.
    van den Brekel, Michiel W. M.
    Del Bon, Francesca
    Nicolai, Piero
    Piazza, Cesare
    Peretti, Giorgio
    CANCERS, 2020, 12 (08) : 1 - 18
  • [45] LARYNGEAL RECONSTRUCTION AND SURVIVAL AFTER FUNCTION-SPARING LARYNGECTOMY FOR SELECTED T3 AND T4 LESIONS
    屠规益
    祈永发
    唐平章
    ChineseMedicalJournal, 1995, (06)
  • [46] LARYNGEAL RECONSTRUCTION AND SURVIVAL AFTER FUNCTION-SPARING LARYNGECTOMY FOR SELECTED T3 AND T4 LESIONS
    TU, GY
    QI, YF
    TANG, PZ
    CHINESE MEDICAL JOURNAL, 1995, 108 (06) : 423 - 427
  • [47] LARYNGEAL RECONSTRUCTION AND SURVIVAL AFTER FUNCTION-SPARING LARYNGECTOMY FOR SELECTED T3 AND T4 LESIONS
    屠规益
    祈永发
    唐平章
    中华医学杂志(英文版), 1995, (06) : 25 - 29
  • [48] Association between cancer surface area and histopathological parameters of laryngeal squamous cell carcinoma in total laryngectomy specimens
    Tomanovic, Nada
    Tomic, Ana Marija
    Mikic, Anton
    Milovanovic, Jovica
    Djordjevic, Vladimir
    Trivic, Aleksandar
    VOJNOSANITETSKI PREGLED, 2022, 79 (09) : 863 - 867
  • [49] Successful 10-year outcomes after supracricoid partial laryngectomy for selected glottic squamous cell carcinoma classified as T3N0M0: A STROBE analysis
    Laccourreye, O.
    Chambrin, G.
    Garcia, D.
    Troux, C.
    Mirghani, H.
    Giraud, P.
    EUROPEAN ANNALS OF OTORHINOLARYNGOLOGY-HEAD AND NECK DISEASES, 2023, 140 (04) : 165 - 170
  • [50] Oncological and functional outcomes in T3 and T4 laryngeal cancer patients: choice for larynx preservation or total laryngectomy based on expected laryngeal function
    Nobacht, Arman
    Meijer, Tineke W. H.
    Oosting, Sjoukje F.
    van der Vegt, Bert
    Wedman, Jan
    Halmos, Gyorgy B.
    Plaat, Boudewijn E. C.
    JOURNAL OF LARYNGOLOGY AND OTOLOGY, 2024, 138 (06): : 672 - 678
12345