Matched-pair analysis of survival in the patients with T3 laryngeal squamous cell carcinoma treated with supracricoid partial laryngectomy or total laryngectomy

被引：8
|
作者：
Xial, Xin [1 ,2 ]
Zhu, Ying-Ying [1 ,2 ]
Diao, Wen-Wen [1 ,2 ]
Zhu, Xiao-Li [1 ,2 ]
Shi, Xiao-Hua [2 ,3 ]
Li, Wu-Yi [1 ,2 ]
Gao, Zhi-Qiang [1 ,2 ]
Li, Guo-Jun [1 ,2 ]
Chen, Xing-Ming [1 ,2 ]
机构：
[1] Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Otolaryngol Head & Neck Surg, 1 Shuaifuyuan, Beijing 100730, Peoples R China
[2] Chinese Acad Med Sci, 1 Shuaifuyuan, Beijing 100730, Peoples R China
[3] Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Pathol, Beijing, Peoples R China
来源：
ONCOTARGETS AND THERAPY | 2018年 / 11卷
关键词：
survival analysis; matched-pair analysis; laryngeal neoplasms; laryngectomy; squamous cell carcinoma; CRICOHYOIDOPEXY; CANCER; CRICOHYOIDOEPIGLOTTOPEXY; PRESERVATION; OUTCOMES; T3-T4;
D O I：
10.2147/OTT.S175358
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Background: The survival outcomes between supracricoid partial laryngectomy (SCPL) and total laryngectomy (TL) were compared in the groups of matched-pair patients with T3 laryngeal squamous cell carcinoma (LSCC). Methods: Patients with T3 LSCC were matched based on prognostic factors. The Kaplan-Meier curve and the Cox proportional hazards model were used for analysis on survival. Results: A total of 212 patients with T3 LSCC were included after matching (106 underwent SCPL and 106 underwent TL). Multivariable analysis showed no differences in overall survival (hazard risk [HR]=1.15; 95% CI: 0.79-1.67; P=0.47), disease-specific survival (HR=1.11; 95% CI: 0.69-1.80; P=0.66), and recurrence-free survival (HR=1.07; 95% CI: 0.68-1.68; P=0.77) between the SCPL group and TL group. Conclusion: SCPL provides reliable therapeutic outcomes and can be used to avoid a TL surgery in sonic patients with advanced primary laryngeal cancer.
引用
收藏
页码：7947 / 7953
页数：7
相关论文
共 50 条
  • [31] Response to definitive chemoradiotherapy and survival in patients with an oesophageal adenocarcinoma versus squamous cell carcinoma: A matched-pair analysis
    Tougeron, David
    Di Fiore, Frederic
    Hamidou, Hadji
    Rigal, Olivier
    Paillot, Bernard
    Michel, Pierre
    ONCOLOGY, 2007, 73 (5-6) : 328 - 334
  • [32] Squamous Cell Carcinoma of the Oral Tongue in the Pediatric Age Group A Matched-Pair Analysis of Survival
    Morris, Luc G. T.
    Patel, Snehal G.
    Shah, Jatin P.
    Ganly, Ian
    ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2010, 136 (07) : 697 - 701
  • [33] Stellenwert der suprakrikoidalen Teilresektion beim moderat fortgeschrittenen Glottiskarzinom (T3–T4a)The value of supracricoid partial laryngectomy in moderately advanced laryngeal cancer (T3–T4a)
    U. Schroeder
    B. Wollenberg
    K. L. Bruchhage
    HNO, 2015, 63 (11) : 741 - 746
  • [34] Results and Survival of Locally Advanced AJCC 7th Edition T4a Laryngeal Squamous Cell Carcinoma Treated with Primary Total Laryngectomy and Postoperative Radiotherapy
    Philippe Gorphe
    Margarida Matias
    Antoine Moya-Plana
    Florian Tabarino
    Pierre Blanchard
    Yungan Tao
    François Janot
    Stéphane Temam
    Annals of Surgical Oncology, 2016, 23 : 2596 - 2601
  • [35] Results and Survival of Locally Advanced AJCC 7th Edition T4a Laryngeal Squamous Cell Carcinoma Treated with Primary Total Laryngectomy and Postoperative Radiotherapy
    Gorphe, Philippe
    Matias, Margarida
    Moya-Plana, Antoine
    Tabarino, Florian
    Blanchard, Pierre
    Tao, Yungan
    Janot, Francois
    Temam, Stephane
    ANNALS OF SURGICAL ONCOLOGY, 2016, 23 (08) : 2596 - 2601
  • [36] Predicting salvage laryngectomy in patients treated with primary nonsurgical therapy for laryngeal squamous cell carcinoma using machine learning
    Smith, Joshua B.
    Shew, Matthew
    Karadaghy, Omar A.
    Nallani, Rohit
    Sykes, Kevin J.
    Gan, Gregory N.
    Brant, Jason A.
    Bur, Andres M.
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2020, 42 (09): : 2330 - 2339
  • [37] Matched-pair analysis of survival in patients with poorly differentiated versus well and moderately differentiated hypopharyngeal squamous cell carcinoma
    Xia, Xin
    Liang, Ya
    Zhu, Yingying
    Zhu, Xiaoli
    Diao, Wenwen
    Chen, Xingming
    MEDICINE, 2022, 101 (27) : E29880
  • [38] Matched-pair analysis of survival in patients with poorly differentiated versus well-differentiated glottic squamous cell carcinoma
    Chen, Ping
    Yu, Wenbin
    Huang, Junwei
    Xu, Hongbo
    Li, Guojun
    Chen, Xiaohong
    Huang, Zhigang
    ONCOTARGET, 2017, 8 (09) : 14770 - 14776
  • [39] Matched-pair analysis of survival of never smokers and ever smokers with squamous cell carcinoma of the head and neck
    Pytynia, KB
    Grant, JR
    Etzel, CJ
    Roberts, DB
    Wei, QY
    Sturgis, EM
    JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (19) : 3981 - 3988
  • [40] Clinical outcome in young patients with squamous cell carcinoma of the oral tongue: A matched-pair analysis
    Park, I. -S.
    Chung, E. -J.
    Lee, D. -J.
    Kim, J. -H.
    Ahn, H. -Y.
    Rho, Y. -S.
    ORAL ONCOLOGY, 2011, 47 : S106 - S106
12345