Ion-selective microelectrode array for intracellular detection on chip

被引：0

作者：

Guenat, OT ^{[1
]}

Wang, XJ ^{[1
]}

Dufour, JF ^{[1
]}

van der Wal, P ^{[1
]}

Morf, WE ^{[1
]}

de Rooij, NF ^{[1
]}

Koudelka-Hep, M ^{[1
]}

机构：

[1] Univ Neuchatel, Inst Microtechnol, Sensors Actuators & Microsyst Lab, CH-2007 Neuchatel, Switzerland

来源：

BOSTON TRANSDUCERS'03: DIGEST OF TECHNICAL PAPERS, VOLS 1 AND 2 | 2003年

关键词：

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

The design and fabrication of an Ion-Selective Electrode (ISE) array platform for in-vitro intracellular recording are presented. The platform is composed of two parts: 1) a glass chip with microchannels whose bottom part is patterned with a silver layer and 2) a silicon chip in which an array of 30 gm long silicon nitride micropipettes with an inner diameter of 1.7 mum are structured: The Ca2(+) selective membrane is based on the neutral carrier ionophore ETH 129. To be compatible with hepatocyte cell cultures the 24 ISEs are arranged in a 2x8 array with 150 mum spacing and four additional electrodes located on both sides of the array at 300 mum.

引用

页码：1063 / 1066

页数：4

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