Adjuvant Systemic Therapy of Breast Cancer

被引：5
|
作者：
Schuetz, Florian [1 ]
机构：
[1] Univ Heidelberg Hosp, Dept Gynecol & Obstet, Heidelberg, Germany
来源：
BREAST CARE | 2011年 / 6卷 / 03期
关键词：
Breast cancer; Adjuvant therapy; Chemotherapy; Endocrine therapy; PREOPERATIVE CHEMOTHERAPY; HIGH-RISK; TRIAL; WOMEN;
D O I：
10.1159/000329336
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The first procedure in primary breast cancer is usually the surgical excision of the tumor. However, a medical therapy is necessary in almost all patients to treat the systemic component of the disease. Which medical approach is recommended depends on the biology of the tumor itself. Endocrine-responsive tumors must be treated by an endocrine therapy according to their menopausal status. In HER2/neu-overexpressing tumors, the monoclonal antibody trastuzumab is part of the standard treatment in combination with chemotherapy. Hormone receptor-negative and non-HER2/neu-overexpressing tumors as well as endocrine-responsive tumors with a high proliferation index or additional risk factors must be treated with chemotherapy as well. This review article gives further information about the available agents and schedules.
引用
收藏
页码：179 / 183
页数：5
相关论文
共 50 条
  • [21] ADJUVANT SYSTEMIC THERAPY FOR EARLY BREAST-CANCER
    CROWN, J
    NORTON, L
    [J]. SEMINARS IN SURGICAL ONCOLOGY, 1991, 7 (05): : 283 - 290
  • [22] ADJUVANT SYSTEMIC THERAPY FOR OPERABLE BREAST-CANCER
    STEWART, HJ
    [J]. BRITISH MEDICAL BULLETIN, 1991, 47 (02) : 343 - 356
  • [23] ADJUVANT SYSTEMIC THERAPY FOR EARLY BREAST-CANCER
    HENDERSON, IC
    [J]. CURRENT PROBLEMS IN CANCER, 1987, 11 (03) : 127 - 207
  • [24] ADJUVANT SYSTEMIC THERAPY IN EARLY BREAST-CANCER
    CANT, ELM
    [J]. AUSTRALIAN AND NEW ZEALAND JOURNAL OF SURGERY, 1976, 46 (04): : 350 - 354
  • [25] Primary and adjuvant systemic therapy for operable breast cancer
    Thomssen, C.
    Huober, J.
    [J]. ONKOLOGE, 2008, 14 (05): : 504 - 513
  • [26] ADJUVANT AND PALLIATIVE SYSTEMIC THERAPY OF BREAST-CANCER
    STOLZENBACH, G
    [J]. PERIODICUM BIOLOGORUM, 1983, 85 : 137 - 155
  • [27] Adjuvant systemic therapy of early stage breast cancer
    William J. Gradishar
    [J]. Current Treatment Options in Oncology, 2003, 4 (2) : 141 - 150
  • [28] ADJUVANT SYSTEMIC THERAPY IN PRIMARY BREAST-CANCER
    MOURIDSEN, HT
    PALSHOF, T
    [J]. ACTA CHIRURGICA SCANDINAVICA, 1984, : 43 - 53
  • [29] Adjuvant systemic therapy for elderly women with breast cancer
    Henry, N. Lynn
    Diehl, Kathleen M.
    Hayes, Daniel F.
    [J]. WOMENS HEALTH, 2006, 2 (01) : 75 - 87
  • [30] ADJUVANT SYSTEMIC THERAPY FOR EARLY BREAST-CANCER
    不详
    [J]. LANCET, 1992, 339 (8784): : 27 - 27
12345