Primary and adjuvant systemic therapy for operable breast cancer

被引:0
|
作者
Thomssen, C. [1 ]
Huober, J. [2 ]
机构
[1] Univ Halle Wittenberg, Klin & Poliklin Gynakol, D-06097 Halle, Saale, Germany
[2] Kantonsspital St Gallen, Senol Zentrum Ostschweiz, St Gallen, Switzerland
来源
ONKOLOGE | 2008年 / 14卷 / 05期
关键词
adjuvant systemic therapy; taxanes; trastuzumab; aromatase inhibitors; bisphosphonates;
D O I
10.1007/s00761-008-1355-8
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The meta-analysis published in 2005 by the EBCTCG showed that the cumulative 15-year mortality rate can be decreased by up to 57% with consistent adjuvant systemic therapy. This analysis only covered the use of medications that have been available up to then - anthracycline-containing triple combination and tamoxifen. By employing taxanes, the antibody trastuzumab, aromatase inhibitors, and bisphosphonates, a further and substantial decrease in mortality can be expected.
引用
收藏
页码:504 / 513
页数:10
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