Miniaturized Electrochemical Immunosensor for Label-Free Detection of Growth Hormone

被引：8
|
作者：
Li, Qi [1 ]
Li, Nan [1 ]
Le Tissier, Paul [2 ]
Grattan, David R. [3 ,4 ]
Kerman, Kagan [1 ]
机构：
[1] Univ Toronto Scarborough, Dept Phys & Environm Sci, Toronto, ON M1C 1A4, Canada
[2] Natl Inst Med Res, Div Mol Neuroendocrinol, London NW7 1AA, England
[3] Univ Otago, Sch Med Sci, Dept Anat & Struct Biol, Dunedin 9001, New Zealand
[4] Univ Otago, Sch Med Sci, Ctr Neuroendocrinol, Dunedin 9001, New Zealand
来源：
ELECTROANALYSIS | 2012年 / 24卷 / 06期
基金：
加拿大自然科学与工程研究理事会;
关键词：
Miniaturization; Immunosensors; Growth hormone; Proteins; Doping; IMMUNOASSAY; INSULIN; SIGNAL; ABUSE;
D O I：
10.1002/elan.201200074
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A miniaturized immunosensor was developed in connection with disposable screen-printed carbon strips (SPCS) for the point-of-care detection of growth hormone. The performance of the miniaturized system was studied using growth hormone (GH) as the target protein and compared with a conventional electrochemical analyzer. The detection limit of 25 pg/mL was observed for GH in 20 mu L sample volume, which indicated that this versatile platform can be easily adapted for decentralized electrochemical immunosensing of clinically important proteins.
引用
收藏
页码：1272 / 1276
页数：5
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