A Label-Free Electrochemical Immunosensor for Detection of Newcastle Disease Virus

被引：0
|
作者：
Tran Quang Thinh [1 ]
Trieu Van Vu Quan [1 ]
Duang, Le Binh [1 ]
Tran Hong Thuy [2 ]
Chu Thi Xuan [2 ]
Mai Anh Tuan [2 ]
机构：
[1] Natl Ctr Technol Progress, Hanoi, Vietnam
[2] Hanoi Univ Sci & Technol, Hanoi, Vietnam
来源：
7TH INTERNATIONAL CONFERENCE ON THE DEVELOPMENT OF BIOMEDICAL ENGINEERING IN VIETNAM (BME7): TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY FOR DEVELOPING COUNTRIES | 2020年 / 69卷
关键词：
Immunosensor; IgY antibody; Newcastle disease virus (NDV); ANTIBODIES; IMMOBILIZATION; ELECTRODES;
D O I：
10.1007/978-981-13-5859-3_118
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
In this study, a label-free electrochemical immunosensor system was designed and fabricated with focus on a detection of Newcastle disease virus (NDV). The chicken egg yolk antibodies (IgY) against NDV was used as the biological recognition element to replace IgG antibody, which offers some advantages with respect to animal care, high productivity and special suitability in the source of antibodies. The IgY against NDV was immobilized on sensor surface using the chemical approach. The immunosensor showed high sensitivity with NDV concentration range from 10(6) to 10(2) EID50/mL. This relatively simple fabrication is potential for applications in infection studies.
引用
收藏
页码：699 / 703
页数：5
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