Effect of dried fruits of Solanum nigrum Linn against CCl4-induced hepatic damage in rats

被引：59
|
作者：
Raju, K [1 ]
Anbuganapathi, G
Gokulakrishnan, V
Rajkapoor, B
Jayakar, B
Manian, S
机构：
[1] Kandaswami Kandars Coll, Dept Bot, PG & Res, Namakkal 638182, Tamil Nadu, India
[2] Kandaswami Kandars Coll, Dept Zool, PG & Res, Namakkal 638182, Tamil Nadu, India
[3] Vinayaka Missions Coll Pharm, Dept Pharmacol, Salem 636008, Tamil Nadu, India
[4] Bharathiar Univ, Dept Bot, Coimbatore 641046, Tamil Nadu, India
来源：
BIOLOGICAL & PHARMACEUTICAL BULLETIN | 2003年 / 26卷 / 11期
关键词：
Solanum nigrum; carbon tetrachloride (CCl4); hepatoprotective activity;
D O I：
10.1248/bpb.26.1618
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Ethanol extract of Solanum nigrum LINN was investigated for its hepatoprotective activity against CCl4-induced hepatic damage in rats. The ethanol extract showed remarkable hepatoprotective activity. The activity was evaluated using biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP) and total bilirubin. The histopathological changes of liver sample in treated animals were compared with respect to control.
引用
收藏
页码：1618 / 1619
页数：2
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