Effect of dried fruits of Solanum nigrum Linn against CCl4-induced hepatic damage in rats

被引：59
|
作者：
Raju, K [1 ]
Anbuganapathi, G
Gokulakrishnan, V
Rajkapoor, B
Jayakar, B
Manian, S
机构：
[1] Kandaswami Kandars Coll, Dept Bot, PG & Res, Namakkal 638182, Tamil Nadu, India
[2] Kandaswami Kandars Coll, Dept Zool, PG & Res, Namakkal 638182, Tamil Nadu, India
[3] Vinayaka Missions Coll Pharm, Dept Pharmacol, Salem 636008, Tamil Nadu, India
[4] Bharathiar Univ, Dept Bot, Coimbatore 641046, Tamil Nadu, India
来源：
BIOLOGICAL & PHARMACEUTICAL BULLETIN | 2003年 / 26卷 / 11期
关键词：
Solanum nigrum; carbon tetrachloride (CCl4); hepatoprotective activity;
D O I：
10.1248/bpb.26.1618
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Ethanol extract of Solanum nigrum LINN was investigated for its hepatoprotective activity against CCl4-induced hepatic damage in rats. The ethanol extract showed remarkable hepatoprotective activity. The activity was evaluated using biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP) and total bilirubin. The histopathological changes of liver sample in treated animals were compared with respect to control.
引用
收藏
页码：1618 / 1619
页数：2
相关论文
共 50 条
  • [21] Possible protective effect of kolaviron on CCl4-induced erythrocyte damage in rats
    Adaramoye, OA
    Akinloye, O
    BIOSCIENCE REPORTS, 2000, 20 (04) : 259 - 264
  • [22] Hepatic Protection by Noni Fruit Juice Against CCl4-Induced Chronic Liver Damage in Female SD Rats
    Mian-Ying Wang
    Gary Anderson
    Diane Nowicki
    Jarakae Jensen
    Plant Foods for Human Nutrition, 2008, 63 : 141 - 145
  • [23] Hepatoprotective effects of Portulaca oleracea extract against CCl4-induced damage in rats
    Eidi, Akram
    Mortazavi, Pejman
    Moghadam, Jalal Zarringhalam
    Mardani, Parisa Mousavi
    PHARMACEUTICAL BIOLOGY, 2015, 53 (07) : 1042 - 1051
  • [24] Evaluation of Hepatoprotective Activity of Caralluma europaea Stem Extract against CCl4-Induced Hepatic Damage in Wistar Rats
    Ouassou, Hayat
    Bouhrim, Mohamed
    Daoudi, Nour Elhouda
    Mekhfi, Hassane
    Ziyyat, Abderrahim
    Legssyer, Abdelkhaleq
    Aziz, Mohamed
    Bnouham, Mohamed
    ADVANCES IN PHARMACOLOGICAL AND PHARMACEUTICAL SCIENCES, 2021, 2021
  • [25] SYSTEMIC HISTOPATHOLOGY OF RATS WITH CCL4-INDUCED HEPATIC CIRRHOSIS
    DOI, K
    KURABE, S
    SHIMAZU, N
    INAGAKI, M
    LABORATORY ANIMALS, 1991, 25 (01) : 21 - 25
  • [26] Hepatic protection by noni fruit juice against CCl4-induced chronic liver damage in female SD rats
    Wang, Mian-Ying
    Anderson, Gary
    Nowicki, Diane
    Jensen, Jarakae
    PLANT FOODS FOR HUMAN NUTRITION, 2008, 63 (03) : 141 - 145
  • [27] Bamboo salt attenuates CCl4-induced hepatic damage in Sprague-Dawley rats
    Zhao, Xin
    Song, Jia-Le
    Kil, Jeung-Ha
    Park, Kun-Young
    NUTRITION RESEARCH AND PRACTICE, 2013, 7 (04) : 273 - 280
  • [28] Hepatoprotective Effect of Superfine Particles of Herbal Medicine against CCl4-Induced Acute Liver Damage in Rats
    Cao, Gang
    Li, Qinglin
    Chen, Xiaocheng
    Cai, Hao
    Tu, Sicong
    BIOMED RESEARCH INTERNATIONAL, 2014, 2014
  • [29] The protective effect of HD-03 in CCl4-induced hepatic encephalopathy in rats
    Mitra, SK
    Venkataranganna, MV
    Gopumadhavan, S
    Anturlikar, SD
    Seshadri, SJ
    Udupa, UV
    PHYTOTHERAPY RESEARCH, 2001, 15 (06) : 493 - 496
  • [30] Therapeutic effect of interleukin-10 on CCl4-induced hepatic fibrosis in rats
    Yue-Hong Huang
    Mei-Na Shi
    Wei-Da Zheng
    Li-Juan Zhang
    Zhi-Xin Chen
    Xiao-Zhong Wang
    WORLD JOURNAL OF GASTROENTEROLOGY, 2006, 12 (09) : 1386 - 1391
12345