Arabidopsis calcium-binding mitochondrial carrier proteins as potential facilitators of mitochondrial ATP-import and plastid SAM-import

被引：44
|
作者：
Stael, Simon [1 ]
Rocha, Agostinho G. [2 ]
Robinson, Alan J. [3 ]
Kmiecik, Przemyslaw [1 ]
Vothknecht, Ute C. [2 ,4 ]
Teige, Markus [1 ]
机构：
[1] Univ Vienna, MFPL, Dept Biochem & Cell Biol, A-1030 Vienna, Austria
[2] Ludwig Maximilians Univ Munchen, Dept Biol 1, D-82152 Planegg Martinsried, Germany
[3] MRC, Mitochondrial Biol Unit, Cambridge CB2 0XY, England
[4] Ludwig Maximilians Univ Munchen, Dept Biol, Ctr Integrated Prot Sci Munich, D-81377 Munich, Germany
来源：
FEBS LETTERS | 2011年 / 585卷 / 24期
基金：
英国医学研究理事会;
关键词：
Chloroplast; Mitochondria; Mitochondrial carrier protein; Calcium-binding; ATP-phosphate carrier; SAM transporter; SUSPENSION-CULTURED CELLS; SACCHAROMYCES-CEREVISIAE; FUNCTIONAL-CHARACTERIZATION; BACTERIAL EXPRESSION; ADP/ATP CARRIER; CYTOSOLIC CA2+; TISSUE DISTRIBUTION; GENE-EXPRESSION; THALIANA; CHLOROPLAST;
D O I：
10.1016/j.febslet.2011.10.039
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Chloroplasts and mitochondria are central to crucial cellular processes in plants and contribute to a whole range of metabolic pathways. The use of calcium ions as a secondary messenger in and around organelles is increasingly appreciated as an important mediator of plant cell signaling, enabling plants to develop or to acclimatize to changing environmental conditions. Here, we have studied the four calcium-dependent mitochondrial carriers that are encoded in the Arabidopsis genome. An unknown substrate carrier, which was previously found to localize to chloroplasts, is proposed to present a calcium-dependent S-adenosyl methionine carrier. For three predicted ATP/phosphate carriers, we present experimental evidence that they can function as mitochondrial ATP-importers. (C) 2011 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
引用
收藏
页码：3935 / 3940
页数：6
相关论文
共 43 条
  • [21] The essential metal binding protein Mia40 mediates import of proteins into the mitochondrial intermembrane space
    Hell, K
    Terziyska, N
    Lutz, T
    Kozany, C
    Mokranjac, D
    Mesecke, N
    Neupert, W
    Herrmann, J
    FASEB JOURNAL, 2005, 19 (04): : A273 - A273
  • [22] Import of rat mitochondrial citrate carrier (CIC) at increasing salt concentrations promotes presequence binding to import receptor Tom20 and inhibits membrane translocation
    Zara, V
    Ferramosca, A
    Papatheodorou, P
    Palmieri, F
    Rassow, J
    JOURNAL OF CELL SCIENCE, 2005, 118 (17) : 3985 - 3995
  • [23] Positively charged amino acids at the N terminus of select mitochondrial proteins mediate early recognition by import proteins αβ'-NAC and Sam37
    Avendano-Monsalve, Maria Clara
    Mendoza-Martinez, Ariann E.
    Ponce-Rojas, Jose Carlos
    Poot-Hernandez, Augusto Cesar
    Rincon-Heredia, Ruth
    Funes, Soledad
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2022, 298 (06)
  • [24] The cytotoxic action of Bax on yeast cells does not require mitochondrial ADP/ATP carrier but may be related to its import to the mitochondria
    Kissová, I
    Polcic, P
    Kempná, P
    Zeman, I
    Sabová, L
    Kolarov, J
    FEBS LETTERS, 2000, 471 (01) : 113 - 118
  • [25] Mitochondrial import of the ADP/ATP carrier:: The essential TIM complex of the intermembrane space is required for precursor release from the TOM complex
    Truscott, KN
    Wiedemann, N
    Rehling, P
    Müller, H
    Meisinger, C
    Pfanner, N
    Guiard, B
    MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (22) : 7780 - 7789
  • [26] Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins
    Koehler, CM
    Merchant, S
    Oppliger, W
    Schmid, K
    Jarosch, E
    Dolfini, L
    Junne, T
    Schatz, G
    Tokatlidis, K
    EMBO JOURNAL, 1998, 17 (22): : 6477 - 6486
  • [27] HP30-2,a mitochondrial PRAT protein for import of signal sequence-less precursor proteins in Arabidopsis thaliana
    Claudia Rossig
    John Gray
    Oscar Valdes
    Sachin Rustgi
    Diter von Wettstein
    Christiane Reinbothe
    Steffen Reinbothe
    Journal of Integrative Plant Biology, 2017, 59 (08) : 535 - 551
  • [28] HP30-2, a mitochondrial PRAT protein for import of signal sequence-less precursor proteins in Arabidopsis thaliana
    Rossig, Claudia
    Gray, John
    Valdes, Oscar
    Rustgi, Sachin
    von Wettstein, Diter
    Reinbothe, Christiane
    Reinbothe, Steffen
    JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2017, 59 (08) : 535 - 551
  • [29] A MITOCHONDRIAL IMPORT FACTOR PURIFIED FROM RAT-LIVER CYTOSOL IS AN ATP-DEPENDENT CONFORMATIONAL MODULATOR FOR PRECURSOR PROTEINS
    HACHIYA, N
    ALAM, R
    SAKASEGAWA, Y
    SAKAGUCHI, M
    MIHARA, K
    OMURA, T
    EMBO JOURNAL, 1993, 12 (04): : 1579 - 1586
  • [30] Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABC-me)
    Graf, SA
    Haigh, SE
    Corson, ED
    Shirihai, OS
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (41) : 42954 - 42963
12345