Asthma;
Lead poisoning;
Comorbidity;
Immunoregulation;
Environmental health disparities;
PREVALENCE;
D O I:
10.1016/j.envres.2010.11.007
中图分类号:
X [环境科学、安全科学];
学科分类号:
08 ;
0830 ;
摘要:
Objective: We sought to ascertain whether asthmatic children are more likely to have elevated blood lead levels (EBLLs), BLLs >= 10 mu g/dL, than non-asthmatic children. Household risk factors associated with both lead and asthma were examined. Method: We undertook a cross-sectional study involving children residing in mainly low-income and minority households in Michigan which were identified by the Statewide Systemic Tracking of Elevated Lead Levels and Remediation database (STELLAR) (n=356 children). Results: Of the 356 index children, 19% had EBLLs and 15% were doctor-diagnosed asthmatic. After adjusting for confounders known to be related to lead poisoning and/or asthma, association remained between asthmatic children and EBLL children (AOR: 5.17; 95% CI (1.25-21.37)). Conclusions: The results of our study show that asthmatic children are over 5 times more likely to have EBLLs than non-asthmatics (AOR: 5.17; 95% CI (1.25-21.37)). Intervention strategies designed to address lead poisoning prevention may be effective in reducing incidence of asthma. Further study is required. (C) 2010 Elsevier Inc. All rights reserved.
机构:
Univ Kansas, Med Ctr, Dept Prevent Med & Publ Hlth, Kansas City, KS 66160 USAUniv Kansas, Med Ctr, Dept Prevent Med & Publ Hlth, Kansas City, KS 66160 USA
James, Aimee
Greiner, K. Allen
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kansas, Med Ctr, Dept Family Med, Kansas City, KS 66160 USAUniv Kansas, Med Ctr, Dept Prevent Med & Publ Hlth, Kansas City, KS 66160 USA
机构:
Northwestern Univ, Feinberg Sch Med, Dept Med Social Sci, Chicago, IL 60611 USANorthwestern Univ, Feinberg Sch Med, Dept Med Social Sci, Chicago, IL 60611 USA
Byck, Gayle R.
Bolland, John
论文数: 0引用数: 0
h-index: 0
机构:
Univ Alabama, Coll Human Environm Sci, Tuscaloosa, AL 35487 USANorthwestern Univ, Feinberg Sch Med, Dept Med Social Sci, Chicago, IL 60611 USA
Bolland, John
Dick, Danielle
论文数: 0引用数: 0
h-index: 0
机构:
Virginia Commonwealth Univ, Dept Psychiat, Virginia Inst Psychiat & Behav Genet, Richmond, VA 23298 USANorthwestern Univ, Feinberg Sch Med, Dept Med Social Sci, Chicago, IL 60611 USA
Dick, Danielle
Ashbeck, Alan W.
论文数: 0引用数: 0
h-index: 0
机构:
Northwestern Univ, Feinberg Sch Med, Dept Med Social Sci, Chicago, IL 60611 USANorthwestern Univ, Feinberg Sch Med, Dept Med Social Sci, Chicago, IL 60611 USA
Ashbeck, Alan W.
Mustanski, Brian S.
论文数: 0引用数: 0
h-index: 0
机构:
Northwestern Univ, Feinberg Sch Med, Dept Med Social Sci, Chicago, IL 60611 USANorthwestern Univ, Feinberg Sch Med, Dept Med Social Sci, Chicago, IL 60611 USA