Synthetic study towards Ieodomycin B by using Evans auxiliary

被引：0
|
作者：
Zhang, Jianting [1 ]
Zhang, Zhibing [1 ]
Lin, Shuangjie [1 ]
Wang, Xiaoji [1 ]
Huang, Shuangping [1 ]
Wang, Rui [2 ]
机构：
[1] Jiangxi Sci & Technol Normal Univ, Sch Pharm, Nanchang, Jiangxi, Peoples R China
[2] Jiangxi Sci & Technol Normal Univ, Sch Chem & Chem Engn, Nanchang, Jiangxi, Peoples R China
来源：
ADVANCES IN ENERGY SCIENCE AND EQUIPMENT ENGINEERING | 2015年
关键词：
STEREOSELECTIVE TOTAL-SYNTHESIS; MARINE; REACTIVITY; ALPHA; ALDEHYDES;
D O I：
暂无
中图分类号：
TE [石油、天然气工业]; TK [能源与动力工程];
学科分类号：
0807 ; 0820 ;
摘要：
The intermediate, 1-(benzo[d][1,3]dioxol-5-yl)prop-2-en-1-one 4, of the total synthesis of norlignans, hyperione A and hyperione B which are demonstrated to have therapeutic effect to fever, hepatitis, and sepsis, was synthesized. The synthetic route of 4 started from commercially available piperonyl alcohol and proceeded through a key Grignard addition and selective oxidation of the allylic alcohol.
引用
收藏
页码：1953 / 1956
页数：4
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