Synthetic Study towards Entecavir

被引：0
|
作者：
Lin, Shuangjie [1 ]
Huang, Feifei [1 ]
Yang, Shenkun [1 ]
Huang, Shuangping [1 ]
Wang, Xiaoji [1 ]
机构：
[1] Jiangxi Sci & Technol Normal Univ, Sch Pharm, Nanchang 330013, Jiangxi, Peoples R China
来源：
PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON ADVANCES IN ENERGY, ENVIRONMENT AND CHEMICAL ENGINEERING | 2015年 / 23卷
关键词：
Entecavir; synthesis; HBV; HEPATITIS-B; BMS-200475; POTENT;
D O I：
暂无
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
A synthetic design of Entecavir was described, and the intermediate, (S)-N-methoxy -3-((4-methoxybenzyl)oxy)-N-methylpent-4-enamide, was synthesized using acrylaldehyde as the starting material, which was obtained via an Evans Aldol reaction, Weinreb amide formation, and a PMB protection.
引用
收藏
页码：840 / 843
页数：4
相关论文
共 50 条
  • [1] A New Formal Synthetic Route to Entecavir
    Liu, Lixia
    Sun, Yongli
    Wang, Jiwu
    Ou, Wentao
    Wang, Xiaoji
    Huang, Shuangping
    SYNLETT, 2019, 30 (06) : 748 - 752
  • [2] Synthetic study towards Verbalactone
    Wang, Liping
    Leng, Xiao
    Qin, Shuanglin
    Huang, Feifei
    Wang, Xiaoji
    Huang, Shuangping
    ADVANCES IN ENERGY SCIENCE AND EQUIPMENT ENGINEERING, 2015, : 315 - 318
  • [3] Synthetic Study towards (-)-Allosedridine
    Huang, Feifei
    Zhang, Zhibin
    Lin, Shuangjie
    Huang, Shuangping
    Wang, Xiaoji
    PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON ADVANCES IN ENERGY, ENVIRONMENT AND CHEMICAL ENGINEERING, 2015, 23 : 828 - 831
  • [4] Synthetic Study towards (±)leodomycin A
    Zhang Jian-Ting
    Chen Shi-Peng
    Zhu Cheng-Lin
    Feng Jun-Min
    Wang Xiao-Ji
    Huang Shuang-Ping
    CHEMICAL, MATERIAL AND METALLURGICAL ENGINEERING III, PTS 1-3, 2014, 881-883 : 423 - 425
  • [5] Synthetic Study towards (±)-Vertine and (±)-Lythrine
    Lin, Shuangjie
    Leng, Xiao
    Zhang, Zhibing
    Huang, Feifei
    Huang, Shuangping
    Wang, Xiaoji
    PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON ADVANCES IN ENERGY, ENVIRONMENT AND CHEMICAL ENGINEERING, 2015, 23 : 836 - 839
  • [6] A Synthetic Study towards the Marmycins and Analogues
    Caneque, Tatiana
    Gomes, Filipe
    Trang Thi Mai
    Blanchard, Florent
    Retailleau, Pascal
    Gallard, Jean-Francois
    Maestri, Giovanni
    Malacria, Max
    Rodriguez, Raphael
    SYNTHESIS-STUTTGART, 2017, 49 (03): : 587 - 592
  • [7] SYNTHETIC STUDY OF AN INTERMEDIATE TOWARDS PARACENTRONE
    Kaneyama, Taiki
    Fujimaru, Kazumi
    Takemura, Mami
    Hasegawa, Kizuku
    Hamada, Masahiro
    Kishimoto, Takao
    Urabe, Daisuke
    Nakajima, Noriyuki
    HETEROCYCLES, 2019, 98 (02) : 281 - 294
  • [8] A STUDY DIRECTED TOWARDS THE DEVELOPMENT OF SYNTHETIC VACCINES
    VANBOOM, JH
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1991, 202 : 55 - CARB
  • [9] SYNTHETIC STUDY TOWARDS THE TETRACYCLIC QUASSINOID SKELETON
    SHING, TKM
    TANG, Y
    TETRAHEDRON, 1990, 46 (06) : 2187 - 2194
  • [10] Synthetic Study towards Strictamine: The Oxidative Coupling Approach
    Ren, Weiwu
    Tappin, Nicholas
    Wang, Qian
    Zhu, Jieping
    SYNLETT, 2013, 24 (15) : 1941 - 1944
12345