Hydrogen peroxide-mediated killing of Caenorhabditis elegans:: a common feature of different streptococcal species

被引:40
|
作者
Bolm, M
Jansen, WTM
Schnabel, R
Chhatwal, GS
机构
[1] GBF, Dept Microbial Pathogenesis & Vaccine Res, German Res Ctr Biotechnol, D-38124 Braunschweig, Germany
[2] Univ Utrecht, Med Ctr, NL-3584 CX Utrecht, Netherlands
[3] Tech Univ Braunschweig, Genet Inst, D-38106 Braunschweig, Germany
关键词
D O I
10.1128/IAI.72.2.1192-1194.2004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Recently, we reported that Streptococcus pyogenes kills Caenorhabditis elegans by the use of hydrogen peroxide (H2O2). Here we show that diverse streptococcal species cause death of C elegans larvae in proportion to the level of H2O2 produced. H2O2 may mask the effects of other pathogenicity factors of catalase-negative bacteria in the C. elegans infection model.
引用
收藏
页码:1192 / 1194
页数:3
相关论文
共 50 条
  • [41] Modulation of sensory perception by hydrogen peroxide enables Caenorhabditis elegans to find a niche that provides both food and protection from hydrogen peroxide
    Schiffer, Jodie A.
    Stumbur, Stephanie V.
    Seyedolmohadesin, Maedeh
    Xu, Yuyan
    Serkin, William T.
    McGowan, Natalie G.
    Banjo, Oluwatosin
    Torkashvand, Mahdi
    Lin, Albert
    Hosea, Ciara N.
    Assie, Adrien
    Samuel, Buck S.
    O'Donnell, Michael P.
    Venkatachalam, Vivek
    Apfeld, Javier
    PLOS PATHOGENS, 2021, 17 (12)
  • [42] Hydrogen peroxide-mediated neuronal cell death induced by an endogenous neurotoxin, 3-hydroxykynurenine
    Okuda, S
    Nishiyama, N
    Saito, H
    Katsuki, H
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (22) : 12553 - 12558
  • [43] Hydrogen peroxide-mediated oxidative stress and collagen synthesis in cardiac fibroblasts: Blockade by tanshinone IIA
    Wang, Ping
    Zhou, Sigui
    Xu, Lipeng
    Lu, Yao
    Yuan, Xi
    Zhang, Huijie
    Li, Ruifang
    Fang, Jian
    Liu, Peiqing
    JOURNAL OF ETHNOPHARMACOLOGY, 2013, 145 (01) : 152 - 161
  • [44] Nitric oxide exacerbates hydrogen peroxide-mediated endothelial permeability through formation of oxidants.
    Okayama, N
    Correia, L
    Grisham, MB
    Kevil, CG
    Jourdheuil, D
    Alexander, JS
    GASTROENTEROLOGY, 1997, 112 (04) : A1055 - A1055
  • [45] Neuroprotective Effect of Isobenzofuranones on Hydrogen Peroxide-Mediated Redox Imbalance in Primary Cultures of Hippocampal Neurons
    Lellis Ribeiro, Lara Mariana
    Machado Oliveira, Laser Antonio
    Pereira, Wagner Luiz
    Teixeira, Robson Ricardo
    Nogueira, Leonardo Brandao
    Pinto Coelho Nogueira, Katiane de Oliveira
    BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY, 2020, 63
  • [46] Hydrogen peroxide-mediated protein oxidation in young and old human MRC-5 fibroblasts
    Merker, K
    Sitte, N
    Grune, T
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2000, 375 (01) : 50 - 54
  • [47] Sodium Iodide/Hydrogen Peroxide-Mediated Oxidation/Lactonization for the Construction of Spirocyclic Oxindole-Lactones
    Li, Guofeng
    Huang, Liwu
    Xu, Jiecheng
    Sun, Wangsheng
    Xie, Junqiu
    Hong, Liang
    Wang, Rui
    ADVANCED SYNTHESIS & CATALYSIS, 2016, 358 (18) : 2873 - 2877
  • [48] SUSCEPTIBILITY OF PLASMA TO FERROUS IRON HYDROGEN PEROXIDE-MEDIATED OXIDATION - DEMONSTRATION OF A POSSIBLE FENTON REACTION
    AGIL, A
    FULLER, CJ
    JIALAL, I
    CLINICAL CHEMISTRY, 1995, 41 (02) : 220 - 225
  • [49] Nitric oxide exacerbates hydrogen peroxide-mediated neutrophil adherence to cultured endothelial monolayers.
    Okayama, N
    Ichikawa, H
    Coe, L
    Alexander, JS
    FASEB JOURNAL, 1998, 12 (04): : A100 - A100
  • [50] An inserted loop region of stromal ascorbate peroxidase is involved in its hydrogen peroxide-mediated inactivation
    Kitajima, Sakihito
    Tomizawa, Ken-ichi
    Shigeoka, Shigeru
    Yokota, Akiho
    FEBS JOURNAL, 2006, 273 (12) : 2704 - 2710