Chemical constituents from the aerial parts of Lippia nodiflora Linn.

被引:8
|
作者
Siddliqui, Bina S. [1 ,2 ]
Ahmad, Fayaz [1 ,2 ]
Sattar, Foulzia A. [1 ,2 ]
Begum, Sabira [1 ,2 ]
机构
[1] Univ Karachi, Int Ctr Chem Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan
[2] Univ Karachi, Dr Panjwani Ctr Mol Med & Drug Res, Karachi 75270, Pakistan
关键词
Lippia nodiflora; Verbenaceae; triterpenoid; rengyolone or halleridone;
D O I
10.1007/BF02977318
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Phytochemical investigation of the methanolic extract of the aerial parts of Lippia nodiflora Linn. led to the isolation of a new triterpenoid lippiacin (1) and a benzofuranone rengyolone (halleridone, 2) through repeated silica gel column chromatography and semi preparative HPLC. The structures of these compounds were determined by spectroscopic methods, including 1COSY-4D and 2D NMR, as well as by comparison with published data. A complete assignment of the H-1- and C-13-NMR data of 2 is reported based on 2D NMR (COSY-45, HMQC and HMBC) spectroscopic methods.
引用
收藏
页码:1507 / 1510
页数:4
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