The Effect of Salpingectomy on Ovarian Reserve and Ovarian Function

Background The effect of salpingectomy on ovarian reserve and ovarian function is still a controversial issue, and more investigations are needed. Objective The aim of this study was to determine the effect of salpingectomy on ovarian reserve and ovarian function. Study Strategy PubMed, Embase, Medline, Web of Knowledge, and the Cochrane trial register were searched. Selection Criteria Studies must have similar study method and be published in English; clear data can be extracted from full test. Data Collection and Analysis Data were collected and analyzed by Review Manager 5.3. Main Results A total of 13 studies were eligible. The level of anti-mullerian hormone is lower, and early follicular phase follicle-stimulating hormone is higher in salpingectomy groups. The level of early follicular phase estradiol and the ovarian volume of salpingectomy groups are the same as control. The total dose of follicle-stimulating hormone needed during in vitro fertilization and embryo transfer (IVF-ET) treatment cycles, the number of collected oocytes, and the clinical pregnancy rate are similar in salpingectomy and control groups. Conclusions Salpingectomy does not appear to affect ovarian function, ovarian response to gonadotropin stimulation, or outcome of IVF-ET in the short run. It may, however, impair ovarian reserve in the long run. Target Audience Obstetricians and gynecologists, family physicians. Learning Objectives After completing this activity, the learner should be better able to understand that salpingectomy does not appear to affect ovarian function, ovarian response to gonadotropin stimulation, or outcome of IVF-ET in the short run, but it may impair ovarian reserve in the long run; understand that ovarian serous cancers may originate from the secretory cells of the fallopian tube; and discuss with patients about the effect of salpingectomy on ovarian reserve and the possibility of ovarian serous cancers before performing salpingectomy.