Magnetizable solid-phase supports for purification of nucleic acids

被引:16
|
作者
Bruce, IJ [1 ]
Davies, MJ [1 ]
Howard, K [1 ]
Smethurst, DE [1 ]
Todd, M [1 ]
机构
[1] UNIV GREENWICH,SCH BIOL & CHEM SCI,LONDON SE18 6PF,ENGLAND
关键词
D O I
10.1111/j.2042-7158.1996.tb07113.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
A simple, small scale non-hazardous procedure for the production of magnetizable solid-phase support (MSPS) beads has been developed based on the extrusion of agarose/iron oxide mixtures. The MSPS beads were derivatized using various amine ligands. Derivatized MSPS beads were used to adsorb nucleic acids from aqueous solution and to separate RNA/DNA mixtures.
引用
收藏
页码:147 / 149
页数:3
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