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Magnetizable solid-phase supports for purification of nucleic acids
被引:16
|作者:
Bruce, IJ
[1
]
Davies, MJ
[1
]
Howard, K
[1
]
Smethurst, DE
[1
]
Todd, M
[1
]
机构:
[1] UNIV GREENWICH,SCH BIOL & CHEM SCI,LONDON SE18 6PF,ENGLAND
关键词:
D O I:
10.1111/j.2042-7158.1996.tb07113.x
中图分类号:
R9 [药学];
学科分类号:
1007 ;
摘要:
A simple, small scale non-hazardous procedure for the production of magnetizable solid-phase support (MSPS) beads has been developed based on the extrusion of agarose/iron oxide mixtures. The MSPS beads were derivatized using various amine ligands. Derivatized MSPS beads were used to adsorb nucleic acids from aqueous solution and to separate RNA/DNA mixtures.
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页码:147 / 149
页数:3
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