Highly reactive 4-membered ring nitrogen-containing heterocycles: Synthesis and properties

被引：0

作者：

Alcaide, Benito ^{[1
]}

Almendros, Pedro ^{[2
]}

Aragoncillo, Cristina ^{[1
]}

机构：

[1] Univ Complutense Madrid, Dept Quim Organ 1, Grp Lactamas & Heterociclos Bioact, Unidad Asociada CSIC, E-28040 Madrid, Spain

[2] CSIC, Inst Quim Organ Gen, E-28006 Madrid, Spain

来源：

CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT | 2010年 / 13卷 / 06期

关键词：

Azetidine; beta-lactam; heterocycle; rearrangement; stereoselectivity; strain; BETA-LACTAMS; BUILDING-BLOCKS; BIOLOGICAL EVALUATION; ASYMMETRIC-SYNTHESIS; STAUDINGER REACTION; KAINIC ACID; KETENES; 2-AZETIDINONES; CYCLOADDITION; INHIBITORS;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

4-Membered nitrogen-containing heterocycles, such as beta-lactams (ie, 2-azetidinones) and azetidines, are useful substrates in organic chemistry for the design and preparation of biologically active compounds by functionalization of the different positions of the ring. In addition, these compounds are versatile building blocks for the synthesis of other types of nitrogen-containing compounds with potential biological properties. This review summarizes recent data regarding the preparation and properties of 4-membered nitrogen-containing heterocyclic rings, as well as their biological activities.

引用

页码：685 / 697

页数：13

共 50 条

[1] Chiral diaziridines for the synthesis of five-membered ring nitrogen-containing heterocycles
Lizza, Joseph
Moura-Letts, Gustavo
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
[2] Diastereoselective cycloaddtions for the synthesis of five-membered ring nitrogen-containing heterocycles
Moura-Letts, Gustavo
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
[3] SYNTHESIS AND STRUCTURE OF A 4-MEMBERED TELLURIUM NITROGEN RING
MUNZENBERG, J
NOLTEMEYER, M
ROESKY, HW
CHEMISCHE BERICHTE, 1989, 122 (10) : 1915 - 1916
[4] REARRANGEMENT REACTIONS IN 4-MEMBERED RING PHOSPHORUS HETEROCYCLES
CREMER, SE
CHORVAT, RJ
TETRAHEDRON LETTERS, 1968, (04) : 413 - &
[5] Synthesis of five-membered nitrogen-containing heterocycles using copper
Navjeet Kaur
Meenu Devi
Pooja Grewal
Neha Ahlawat
Pranshu Bhardwaj
Yamini Verma
Nirmala Kumari Jangid
Journal of the Iranian Chemical Society, 2022, 19 : 679 - 727
[6] Synthesis of five-membered nitrogen-containing heterocycles using copper
Kaur, Navjeet
Devi, Meenu
Grewal, Pooja
Ahlawat, Neha
Bhardwaj, Pranshu
Verma, Yamini
Jangid, Nirmala Kumari
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2022, 19 (03) : 679 - 727
[7] SYNTHESIS OF 4-MEMBERED AND 8-MEMBERED HETEROCYCLES CONTAINING SULFUR, NITROGEN AND PHOSPHORUS AND THE X-RAY STRUCTURE OF A PHOSPHORUS-CONTAINING 8-MEMBERED SN-RING
ROESKY, HW
MEHROTRA, SK
PLATTE, C
AMIRZADEHASL, D
ROTH, B
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 1980, 35 (09): : 1130 - 1136
[8] PLATINUM COMPLEX CONTAINING A 4-MEMBERED RING
ALNAJJAR, IM
GREEN, M
KERRISON, SJS
SADLER, PJ
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1979, (07) : 311 - 312
[9] Formation of nitrogen-containing six-membered heterocycles on steroidal ring system: A review
Sharma, Kamlesh
Kumar, Himanshi
Priyanka
STEROIDS, 2023, 191
[10] THE SYNTHESIS OF 5-MEMBERED AND 6-MEMBERED NITROGEN-CONTAINING HETEROCYCLES FROM IMINOESTERS
KELAREV, VI
KOSHELEV, VN
USPEKHI KHIMII, 1995, 64 (04) : 339 - 372

← 1 2 3 4 5 →