Synthesis of enantiomerically pure (-)-(S)-brevicolline

被引：18
|
作者：
Mahboobi, S [1 ]
Wiegrebe, W [1 ]
Popp, A [1 ]
机构：
[1] Univ Regensburg, Inst Pharm, D-93040 Regensburg, Germany
来源：
JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 04期
关键词：
D O I：
10.1021/np980492h
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
(-)-(S)-Brevicolline (1) and related beta-carbolines were synthesized using an enantiomerically pure Michael-acceptor synthon (3). Subsequent Pictet-Spengler reaction afforded the tetrahydro-beta-carboline skeleton, which, in turn, was transformed to the beta-carboline by catalytic dehydrogenation.
引用
收藏
页码：577 / 579
页数：3
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