Synthesis of enantiomerically pure (-)-(S)-brevicolline

被引：18

作者：

Mahboobi, S ^{[1
]}

Wiegrebe, W ^{[1
]}

Popp, A ^{[1
]}

机构：

[1] Univ Regensburg, Inst Pharm, D-93040 Regensburg, Germany

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 04期

关键词：

D O I：

10.1021/np980492h

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

(-)-(S)-Brevicolline (1) and related beta-carbolines were synthesized using an enantiomerically pure Michael-acceptor synthon (3). Subsequent Pictet-Spengler reaction afforded the tetrahydro-beta-carboline skeleton, which, in turn, was transformed to the beta-carboline by catalytic dehydrogenation.

引用

页码：577 / 579

页数：3

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