Acute sensory ataxic neuropathy associated with monospecific anti-GD1b IgG antibody

被引：43
|
作者：
Pan, CL
Yuki, N
Koga, M
Chiang, MC
Hsieh, ST
机构：
[1] Natl Taiwan Univ, Coll Med, Dept Anat & Cell Biol, Taipei 10018, Taiwan
[2] Natl Taiwan Univ Hosp, Dept Neurol, Taipei, Taiwan
[3] Yamaguchi Univ, Sch Med, Dept Neurol, Yamaguchi 753, Japan
来源：
NEUROLOGY | 2001年 / 57卷 / 07期
关键词：
D O I：
10.1212/WNL.57.7.1316
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The authors describe two patients with acute sensory ataxic neuropathy. Both had a profound loss of proprioception and generalized areflexia. High titers of monospecific anti-GD1b IgG antibody were detected in their sera during the acute phase. Sensory ataxia resolved within 2 weeks after the onset. Taken together with the induction of experimental sensory ataxic neuropathy sensitized with GD1b ganglioside, GD1b may be a target molecule for autoantibody in some patients with acute sensory ataxic neuropathy.
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页码：1316 / 1318
页数：3
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