Acute sensory ataxic neuropathy associated with monospecific anti-GD1b IgG antibody

被引:43
|
作者
Pan, CL
Yuki, N
Koga, M
Chiang, MC
Hsieh, ST
机构
[1] Natl Taiwan Univ, Coll Med, Dept Anat & Cell Biol, Taipei 10018, Taiwan
[2] Natl Taiwan Univ Hosp, Dept Neurol, Taipei, Taiwan
[3] Yamaguchi Univ, Sch Med, Dept Neurol, Yamaguchi 753, Japan
关键词
D O I
10.1212/WNL.57.7.1316
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors describe two patients with acute sensory ataxic neuropathy. Both had a profound loss of proprioception and generalized areflexia. High titers of monospecific anti-GD1b IgG antibody were detected in their sera during the acute phase. Sensory ataxia resolved within 2 weeks after the onset. Taken together with the induction of experimental sensory ataxic neuropathy sensitized with GD1b ganglioside, GD1b may be a target molecule for autoantibody in some patients with acute sensory ataxic neuropathy.
引用
收藏
页码:1316 / 1318
页数:3
相关论文
共 50 条
  • [31] Dorsal root enhancement in paraneoplastic sensory ataxic neuropathy with anti-Hu antibody
    Kobayashi, Aya Shibui Junpei
    Kuroda, Hiroshi
    Aoki, Masashi
    NEUROLOGY AND CLINICAL NEUROSCIENCE, 2016, 4 (01): : 22 - 24
  • [32] REACTIVITY OF A HUMAN MONOCLONAL ANTI-GM1 AND ANTI-GD1B IGM ANTIBODY WITH HUMAN NEURONS IN CULTURES
    JAUBERTEAU, MO
    BRINDEL, I
    BAUMANN, N
    PREUDHOMME, JL
    JOURNAL OF NEUROIMMUNOLOGY, 1993, 48 (01) : 53 - 58
  • [33] Acute ophthalmoparesis associated with Anti-GM1, Anti-GD1a, and Anti-GD1b antibodies after enterovirus infection in a 6-year-old girl
    Fusco, Carlo
    Bertani, Gianna
    Scarano, Angela
    Della Giustina, Elvio
    JOURNAL OF CHILD NEUROLOGY, 2007, 22 (04) : 432 - 434
  • [34] Anti-GD1b IgG positive case of overlapping Ficher's and Guillain-Barre syndromes
    Caudie, C
    Schandelong, A
    Rapoport, F
    Vial, C
    ANNALES DE BIOLOGIE CLINIQUE, 2004, 62 (05) : 591 - 594
  • [35] Acute oropharyngeal palsy associated with anti-GM1b IgG antibody
    Ikuta, N
    Fukusako, T
    Yuki, N
    Morimatsu, M
    Koga, M
    JOURNAL OF NEUROLOGY, 2003, 250 (07) : 881 - 882
  • [36] Acute oropharyngeal palsy associated with anti-GM1b IgG antibody
    N. Ikuta
    T. Fukusako
    N. Yuki
    M. Morimatsu
    M. Koga
    Journal of Neurology, 2003, 250 : 881 - 882
  • [37] Anti-GD1b antibody-mediated trkC downregulation of dorsal root ganglia neurons
    Hitoshi, S
    Kusunoki, S
    Tsuji, S
    Kanazawa, I
    ANNALS OF NEUROLOGY, 1998, 44 (03) : 464 - 464
  • [38] Elevation in anti-GQ1b, anti-GT1a, and anti-GT1b IgG antibodies in postinfectious acute ataxic neuropathy with oropharyngeal palsy but without ophthalmolplegia
    Keiko Kamakura
    Ken-ichi Kaida
    Susumu Kusunoki
    Norikazu Miyamoto
    Jun Fukuda
    Kazuo Motoyoshi
    Journal of Neurology, 2000, 247 : 566 - 567
  • [39] Elevation in anti-GQ1b, anti-GT1a, and anti-GT1b IgG antibodies in postinfectious acute ataxic neuropathy with oropharyngeal palsy but without ophthalmoplegia
    Kamakura, K
    Kaida, K
    Kusunoki, S
    Miyamoto, N
    Fukuda, J
    Motoyoshi, K
    JOURNAL OF NEUROLOGY, 2000, 247 (07) : 566 - 567
  • [40] ACUTE MOTOR AXONAL NEUROPATHY ASSOCIATED WITH ANTI-GD1A AND GT1A IGG ANTIBODIES: THE PERFECT STORM
    Acerra, Gabriella Maria
    Serio, Marina
    Della Valle, Paola
    Bevilacqua, Liliana
    Noioso, Ciro Maria
    De Marca, Umberto
    De Biasi, Giuseppe
    Toriello, Antonella
    Iovino, Aniello
    JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2023, 28 : S3 - S4