Acute sensory ataxic neuropathy associated with monospecific anti-GD1b IgG antibody

被引：43
|
作者：
Pan, CL
Yuki, N
Koga, M
Chiang, MC
Hsieh, ST
机构：
[1] Natl Taiwan Univ, Coll Med, Dept Anat & Cell Biol, Taipei 10018, Taiwan
[2] Natl Taiwan Univ Hosp, Dept Neurol, Taipei, Taiwan
[3] Yamaguchi Univ, Sch Med, Dept Neurol, Yamaguchi 753, Japan
来源：
NEUROLOGY | 2001年 / 57卷 / 07期
关键词：
D O I：
10.1212/WNL.57.7.1316
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The authors describe two patients with acute sensory ataxic neuropathy. Both had a profound loss of proprioception and generalized areflexia. High titers of monospecific anti-GD1b IgG antibody were detected in their sera during the acute phase. Sensory ataxia resolved within 2 weeks after the onset. Taken together with the induction of experimental sensory ataxic neuropathy sensitized with GD1b ganglioside, GD1b may be a target molecule for autoantibody in some patients with acute sensory ataxic neuropathy.
引用
收藏
页码：1316 / 1318
页数：3
相关论文
共 50 条
  • [1] Monospecific anti-GD1b IgG is required to induce rabbit ataxic neuropathy
    Kusunoki, S
    Hitoshi, S
    Kaida, K
    Arita, M
    Kanazawa, I
    ANNALS OF NEUROLOGY, 1999, 45 (03) : 400 - 403
  • [2] Features of sensory ataxic neuropathy associated with anti-GD1b IgM antibody
    Susuki, K
    Yuki, N
    Hirata, K
    JOURNAL OF NEUROIMMUNOLOGY, 2001, 112 (1-2) : 181 - 187
  • [3] Postinfection sensory neuropathy associated with IgG anti-GD1b antibody
    Yuki, N
    Hirata, K
    ANNALS OF NEUROLOGY, 1998, 43 (05) : 685 - 687
  • [4] GD1b-induced sensory ataxic neuropathy: Anti-GD1b antibody is an essential pathogenetic factor
    Kusunoki, S
    Hitoshi, S
    Chiba, A
    Murayama, S
    Kanazawa, I
    ANNALS OF NEUROLOGY, 1997, 42 (03) : T268 - T268
  • [5] Ataxic form of Guillain-Barre syndrome associated with anti-GD1b IgG antibody
    Yuki, N
    Susuki, K
    Hirata, K
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2000, 69 (01): : 136 - 137
  • [6] An acute motor and sensory axonal neuropathy with cerebellar ataxia associated with anti-GD1b IgG and anti-GM1 IgG antibodies
    Liu, Zhirong
    Lou, Min
    Mao, Shanying
    NEUROLOGY INDIA, 2010, 58 (05) : 788 - 789
  • [7] Prominent sensory ataxia in Guillain-Barre syndrome associated with IgG anti-GD1b antibody
    Wicklein, EM
    Pfeiffer, G
    Yuki, N
    Hartard, C
    Kunze, K
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 1997, 151 (02) : 227 - 229
  • [8] Rabbit experimental sensory ataxic neuropathy: anti-GD1b antibody-mediated trkC downregulation of dorsal root ganglia neurons
    Hitoshi, S
    Kusunoki, S
    Murayama, S
    Tsuji, S
    Kanazawa, I
    NEUROSCIENCE LETTERS, 1999, 260 (03) : 157 - 160
  • [9] Acute ataxic neuropathy with anti-GD1B and GQ1B antibodies post Campylobacter jejuni infection
    Cm, C
    Notturno, F
    Uncini, A
    JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2006, 11 (02) : 183 - 183
  • [10] Chronic ataxic neuropathies associated with anti-GD1b IgM antibodies: response to IVIg therapy
    Attarian, S.
    Boucraut, J.
    Hubert, A. M.
    Uzenot, D.
    Delmont, E.
    Verschueren, A.
    Franques, J.
    Azulay, J. P.
    Pouget, J.
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2010, 81 (01): : 61 - 64
12345