Two-dimensional Fourier transform ion cyclotron resonance mass spectrometry: reduction of scintillation noise using Cadzow data processing

被引：19
|
作者：
van Agthoven, Maria A. [1 ]
Coutouly, Marie-Aude [2 ]
Rolando, Christian [1 ]
Delsuc, Marc-Andre [2 ,3 ,4 ]
机构：
[1] Univ Lille 1, USR CNRS 3290, Inst Michel Eugene Chevreul, FR CNRS 2638,IFR 147, F-59655 Villeneuve Dascq, France
[2] NMRTEC, F-67400 Illkirch Graffenstaden, France
[3] Univ Strasbourg, Inst Genet & Biol Mol & Cellulaire, INSERM, U596, F-67404 Illkirch Graffenstaden, France
[4] Univ Strasbourg, UMR CNRS 7104, F-67404 Illkirch Graffenstaden, France
来源：
RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 2011年 / 25卷 / 11期
关键词：
ELECTRON-CAPTURE DISSOCIATION; TWO-DIMENSIONAL NMR; HADAMARD-TRANSFORM; T(1) NOISE; ENHANCEMENT PROCEDURE; MAGNETRON MOTION; T1; NOISE; SPECTRA; SPECTROSCOPY; SUPPRESSION;
D O I：
10.1002/rcm.5002
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
In two-dimensional Fourier transformion cyclotron resonance mass spectrometry (2D FTICR-MS), scintillation noise, caused mostly by fluctuations in the number of ions in the ICR cell, is the leading cause for errors in spectrum interpretation. In this study, we adapted an algorithm based on singular value decomposition and first introduced by Cadzow et al. (IEE Proceedings Pt. F 1987, 134, 69) to 2D FTICR-MS and we measured its performance in terms of noise reduction without losing signal information in the 2D mass spectrum. Copyright (C) 2011 John Wiley & Sons, Ltd.
引用
收藏
页码：1609 / 1616
页数：8
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