Total synthesis of Berkeleylactone F

被引：2

作者：

Vakiti, Anantha Reddy ^{[1
,2
]}

Valluru, Krishna Reddy ^{[1
]}

Verma, S. Naresh ^{[2
]}

Syed, Tasqeeruddin ^{[3
]}

Sridhar, Gattu ^{[4
]}

Kumar, J. V. Shanmukha ^{[2
]}

机构：

[1] IDA, GVK Biosci Private Ltd, Med Chem Div 28A, Hyderabad, Telangana, India

[2] Koneru Lakshmaiah Educ Fdn, Dept Chem, Guntur, Andhra Pradesh, India

[3] King Khalid Univ, Coll Pharm, Dept Pharmaceut Chem, Abha, Saudi Arabia

[4] Kakatiya Inst Technol & Sci, Dept Chem, Warangal, Andhra Pradesh, India

来源：

SYNTHETIC COMMUNICATIONS | 2022年 / 52卷 / 02期

关键词：

Berkeleylactone F; polyhydroxylated macrolides; Wittig reaction and Yamaguchi macrolactonization; CHOLESTEROL-BIOSYNTHESIS; SECONDARY METABOLITES; DECARESTRICTINES; PENICILLIUM; INHIBITORS; MACROLIDES; FAMILY; LACTONE;

D O I：

10.1080/00397911.2021.2012804

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient total synthesis of Berkeleylactone F has been synthesized from the known starting materials. The key steps involved in the synthesis are Wittig reaction, epoxide ring opening with 1, 3-dithiane and Yamaguchi macrolactonization.

引用

页码：205 / 211

页数：7

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