Total synthesis of Berkeleylactone F

被引：2
|
作者：
Vakiti, Anantha Reddy [1 ,2 ]
Valluru, Krishna Reddy [1 ]
Verma, S. Naresh [2 ]
Syed, Tasqeeruddin [3 ]
Sridhar, Gattu [4 ]
Kumar, J. V. Shanmukha [2 ]
机构：
[1] IDA, GVK Biosci Private Ltd, Med Chem Div 28A, Hyderabad, Telangana, India
[2] Koneru Lakshmaiah Educ Fdn, Dept Chem, Guntur, Andhra Pradesh, India
[3] King Khalid Univ, Coll Pharm, Dept Pharmaceut Chem, Abha, Saudi Arabia
[4] Kakatiya Inst Technol & Sci, Dept Chem, Warangal, Andhra Pradesh, India
来源：
SYNTHETIC COMMUNICATIONS | 2022年 / 52卷 / 02期
关键词：
Berkeleylactone F; polyhydroxylated macrolides; Wittig reaction and Yamaguchi macrolactonization; CHOLESTEROL-BIOSYNTHESIS; SECONDARY METABOLITES; DECARESTRICTINES; PENICILLIUM; INHIBITORS; MACROLIDES; FAMILY; LACTONE;
D O I：
10.1080/00397911.2021.2012804
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient total synthesis of Berkeleylactone F has been synthesized from the known starting materials. The key steps involved in the synthesis are Wittig reaction, epoxide ring opening with 1, 3-dithiane and Yamaguchi macrolactonization.
引用
收藏
页码：205 / 211
页数：7
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