Transition metal-free annulative vinylene transfer via the 1,3-dipolar reaction of N-ylides: access to benzo-fused indolizines

被引：19

作者：

Zhao, Limin

Li, Wen

Liu, Jiali

Ni, Linying

Liu, Zhihao

Shen, Hao

Cao, Hua

Liu, Xiang ^{[1
]}

机构：

[1] Guangdong Pharmaceut Univ, Sch Chem & Chem Engn, Zhongshan 528458, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2022年 / 20卷 / 48期

关键词：

CARBONATE; CYCLIZATION; STRATEGY; C1;

D O I：

10.1039/d2ob01846b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient metal-free annulative vinylene transfer protocol for the synthesis of benzo-fused indolizines via 1,3-dipolar cycloadditions of N-ylides with vinylene carbonate has been developed. Vinylene carbonate serves as an acetylene surrogate without any external oxidant involved. This transformation leads to the direct construction of versatile benzo-fused indolizine derivatives in moderate to good yields.

引用

页码：9604 / 9608

页数：5

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