Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States

被引:87
|
作者
Endimiani, Andrea [1 ]
Carias, Lenore L. [1 ]
Hujer, Andrea M. [1 ]
Bethel, Christopher R. [1 ]
Hujer, Kristine M. [1 ]
Perez, Federico [2 ,3 ]
Hutton, Rebecca A. [1 ]
Fox, William R. [4 ]
Hall, Geraldine S. [4 ]
Jacobs, Michael R. [5 ]
Paterson, David L. [6 ]
Rice, Louis B. [1 ]
Jenkins, Stephen G. [7 ]
Tenover, Fred C. [8 ]
Bonomo, Robert A. [1 ,9 ]
机构
[1] Vet Affairs Med Ctr, Louis Stokes Cleveland Dept, Res Serv, Infect Dis Sect, Cleveland, OH 44106 USA
[2] Univ Hosp Cleveland, Case Med Ctr, HIV Med, Cleveland, OH 44106 USA
[3] Univ Hosp Cleveland, Case Med Ctr, Div Infect Dis, Cleveland, OH 44106 USA
[4] Cleveland Clin Fdn, Cleveland, OH 44195 USA
[5] Case Western Reserve Univ, Sch Med, Dept Pathol, Cleveland, OH 44106 USA
[6] Univ Pittsburgh, Med Ctr, Pittsburgh, PA 15212 USA
[7] Mt Sinai Med Ctr, New York, NY 10029 USA
[8] Ctr Dis Control & Prevent, Off Antimicrobial Resistance, Atlanta, GA 30333 USA
[9] Case Western Reserve Univ, Sch Med, Dept Pharmacol, Cleveland, OH 44106 USA
关键词
D O I
10.1128/AAC.00158-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The presence of plasmid-mediated quinolone resistance genes [i.e., qnrA, qnrB, qnrS, aac(6')-Ib-cr, and qepA] was evaluated among 42 bla(KPC)-containing Klebsiella pneumoniae isolates collected in the eastern United States. One isolate carried the bla(KPC-3) and qnrB19 genes on the same conjugative plasmid, whereas another carried the bla(KPC-3) and qnrA1 genes on separate plasmids.
引用
收藏
页码:2680 / 2682
页数:3
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