Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States

被引：87

作者：

Endimiani, Andrea ^{[1
]}

Carias, Lenore L. ^{[1
]}

Hujer, Andrea M. ^{[1
]}

Bethel, Christopher R. ^{[1
]}

Hujer, Kristine M. ^{[1
]}

Perez, Federico ^{[2
,3
]}

Hutton, Rebecca A. ^{[1
]}

Fox, William R. ^{[4
]}

Hall, Geraldine S. ^{[4
]}

Jacobs, Michael R. ^{[5
]}

Paterson, David L. ^{[6
]}

Rice, Louis B. ^{[1
]}

Jenkins, Stephen G. ^{[7
]}

Tenover, Fred C. ^{[8
]}

Bonomo, Robert A. ^{[1
,9
]}

机构：

[1] Vet Affairs Med Ctr, Louis Stokes Cleveland Dept, Res Serv, Infect Dis Sect, Cleveland, OH 44106 USA

[2] Univ Hosp Cleveland, Case Med Ctr, HIV Med, Cleveland, OH 44106 USA

[3] Univ Hosp Cleveland, Case Med Ctr, Div Infect Dis, Cleveland, OH 44106 USA

[4] Cleveland Clin Fdn, Cleveland, OH 44195 USA

[5] Case Western Reserve Univ, Sch Med, Dept Pathol, Cleveland, OH 44106 USA

[6] Univ Pittsburgh, Med Ctr, Pittsburgh, PA 15212 USA

[7] Mt Sinai Med Ctr, New York, NY 10029 USA

[8] Ctr Dis Control & Prevent, Off Antimicrobial Resistance, Atlanta, GA 30333 USA

[9] Case Western Reserve Univ, Sch Med, Dept Pharmacol, Cleveland, OH 44106 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 07期

关键词：

D O I：

10.1128/AAC.00158-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The presence of plasmid-mediated quinolone resistance genes [i.e., qnrA, qnrB, qnrS, aac(6')-Ib-cr, and qepA] was evaluated among 42 bla(KPC)-containing Klebsiella pneumoniae isolates collected in the eastern United States. One isolate carried the bla(KPC-3) and qnrB19 genes on the same conjugative plasmid, whereas another carried the bla(KPC-3) and qnrA1 genes on separate plasmids.

引用

页码：2680 / 2682

页数：3

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