Non-food bioactive forest product liriodenine: Sources, chemistry, and bioactivities

被引：6
|
作者：
Huang, Xiaobo [1 ]
Hao, Nan [2 ]
Wang, Qun [1 ]
Li, Ruru [1 ]
Zhang, Ge [1 ]
Chen, Genqiang [1 ]
Liu, Shengming [1 ]
Che, Zhiping [1 ]
机构：
[1] Henan Univ Sci & Technol, Coll Hort & Plant Protect, Luoyang 471023, Henan, Peoples R China
[2] Northwest A&F Univ, Coll Plant Protect, Yangling 712100, Shaanxi, Peoples R China
来源：
INDUSTRIAL CROPS AND PRODUCTS | 2022年 / 187卷
基金：
中国国家自然科学基金;
关键词：
Liriodenine; Plant sources; Synthesis; Structural modification; Bioactivities; ANNONA-DIVERSIFOLIA SAFF; PYRIMIDINE-BETA-CARBOLINE; FACTOR RECEPTOR-BINDING; COLON-CANCER CELLS; APORPHINE ALKALOIDS; CHEMICAL-CONSTITUENTS; OXOAPORPHINE ALKALOIDS; ISOQUINOLINE ALKALOIDS; STEM BARK; CYTOTOXIC CONSTITUENTS;
D O I：
10.1016/j.indcrop.2022.115447
中图分类号：
S2 [农业工程];
学科分类号：
0828 ;
摘要：
Liriodenine, an oxoaporphine-type alkaloid, widely exists in various forest plants as a non-food bioactive natural product. It showed a great diversity of biological effects, such as anticancer, antimicrobial, antiparasitic, insecticidal activities as well as inhibitory effects on topoisomerase and cholinesterase. Additionally, liriodenine possesses a delicate molecular backbone containing planar hydrophobic conjugated system. Thus, it is extremely promising to be developed in pharmaceutical and agrochemical industries. In this review, we systematically summarized its sources, chemistry, and bioactivities. Furthermore, some expectations for the future research and development were prospectively proposed based on the related publications of this field up to May in 2022.
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页数：19
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