Microwave assisted one pot synthesis of 2-alkyl amino benzimidazoles, 2-alkyl amino benzoxazoles and 2-alkyl amino benzthiazoles by using various carbodiimides

被引：4
|
作者：
Rapolu, Thirupathi [1 ,3 ]
Naveen, Polkam [2 ]
Kumar, K. V. P. Pavan [1 ]
Leleti, Krishnakanth Reddy [1 ,4 ]
Korapolu, Raghubabu [3 ]
机构：
[1] GVK Biosci Pvt Ltd, IDA Nacharam, Chem Serv, Hyderabad 500076, India
[2] Jawaharlal Nehru Technol Univ Hyderabad, Ctr Chem Sci & Technol, IST, Hyderabad 500085, Telangana, India
[3] Andhra Univ, Coll Engn A, Dept Engn C, Visakhapatnam 530003, Andhra Pradesh, India
[4] Sai Lifesci Ltd, Med Chem Div, DS-7,ICICI Knowledge Pk, Hyderabad 500078, India
来源：
RESULTS IN CHEMISTRY | 2022年 / 4卷
关键词：
2-aminobenzimidazole; 2-aminobenzoxazole; 2-aminobenzthiazole; Bioisosteres; Carbodiimide; Microwave irradiation technique; PHASE COMBINATORIAL SYNTHESIS; EFFICIENT SYNTHESIS; CATALYZED SYNTHESIS; O-HALOANILINES; SNAR REACTION; DERIVATIVES; 2-AMINOBENZIMIDAZOLES; AMINATION; INDOLES; 2-AMINOBENZOXAZOLES;
D O I：
10.1016/j.rechem.2022.100351
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A library of bioisosteres namely 2-amino substituted benzimidazole, 2-amino substituted benzoxazole, 2-amino substituted benzthiazole derivatives has been synthesized by an efficient ligand free, zinc catalysed one-pot cascade microwave irradiation technique has been developed. The procedure starts with coupling of various carbodiimides with appropriately substituted o-phenylendiamine, o-aminophenol, o-aminothiols to give the corresponding derivatives in excellent yields.
引用
收藏
页数：8
相关论文
共 50 条
  • [1] Microwave assisted synthesis of some 2-alkyl and 2-arylperimidines
    Mobinikhaledi, A
    Amrollahi, MA
    Foroughifar, N
    Jirandehi, HF
    ASIAN JOURNAL OF CHEMISTRY, 2005, 17 (04) : 2411 - 2414
  • [2] Microwave assisted synthesis of 2-alkyl and 2-aryl derivatives of benzimidazole
    Rismpathak, D. D.
    Pal, S. C.
    Mandal, Subhash C.
    Belsare, D. P.
    ASIAN JOURNAL OF CHEMISTRY, 2007, 19 (04) : 3242 - 3244
  • [3] Synthesis of 2-alkyl(aryl)thietanes
    N. P. Volynskii
    S. E. Shevchenko
    Petroleum Chemistry, 2007, 47 (2) : 109 - 117
  • [4] Synthesis of 2-alkyl(aryl)thietanes
    Volynskii, N. P.
    Shevchenko, S. E.
    PETROLEUM CHEMISTRY, 2007, 47 (02) : 109 - 117
  • [5] ENANTIOSELECTIVE SYNTHESIS OF 2-ALKYL SUBSTITUTED CYSTEINES
    PATTENDEN, G
    THOM, SM
    JONES, MF
    TETRAHEDRON, 1993, 49 (10) : 2131 - 2138
  • [6] Synthesis and pharmacology of 2-alkyl raloxifene analogs
    Grese, TA
    Cho, S
    Bryant, HU
    Cole, HW
    Glasebrook, AL
    Magee, DE
    Phillips, DL
    Rowley, ER
    Short, LL
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1996, 6 (02) : 201 - 206
  • [7] GENERAL SYNTHESIS OF 2-ALKYL TETRONIC ACIDS
    DAMON, RE
    LUO, T
    SCHLESSINGER, RH
    TETRAHEDRON LETTERS, 1976, (32) : 2749 - 2752
  • [8] Synthesis of 2-alkyl triazoles with solvothermal conditions
    Ma, Youcai
    Zhang, Xiaohui
    Yang, Yawen
    Hu, Liangzhen
    Xiong, Yan
    TETRAHEDRON, 2022, 113
  • [9] Synthesis and biological evaluation of 2-alkyl benzimidazolyl-6-amino-β-D-glucopyranoses
    Umare, V. D.
    Ingle, V. N.
    Wanare, R. K.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2008, 17 (03) : 253 - 256
  • [10] Conformations of 2-alkyl(aryl)thiocyclohexanones
    Samoshin, VV
    Kudryavtsev, KB
    Yartseva, IV
    Lutsenko, AI
    Zefirov, NS
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2000, 36 (09) : 1279 - 1281
12345