Copper Catalyzed Cross-Coupling of Iodobenzoates with Bromozinc-difluorophosphonate

被引：142
|
作者：
Feng, Zhang [1 ]
Chen, Fei [1 ]
Zhang, Xingang [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China
来源：
ORGANIC LETTERS | 2012年 / 14卷 / 07期
关键词：
ELECTRON-DEFICIENT POLYFLUOROARENES; ARYL IODIDES; BENZYLIC PHOSPHONATES; FACILE SYNTHESIS; FLUORINE; DIFLUOROMETHYLATION; ANALOGS; REAGENT; ZINC; TRIFLUOROMETHYLATION;
D O I：
10.1021/ol3006425
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A copper-catalyzed cross-coupling of iodobenzoates with bromozinc-difluorophosphonate, generated from diethyl bromodifluoromethylphosphonate and zinc in dioxane, is reported. The notable features of this reaction are its high reaction efficiency, excellent functional group compatibility, and operational simplicity. This protocol provides a useful and facile access to aryldifluorophosphonates of interest in life science.
引用
收藏
页码：1938 / 1941
页数：4
相关论文
共 50 条
  • [31] Copper-catalyzed cross-coupling of arylsulfonyl chlorides with arylboronic acids
    Hu, Feng
    Lei, Xiangyang
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [32] Copper-Catalyzed Cross-Coupling of Alkylsamarium Reagents with Alkyl Halides
    Tetrahedron Lett, 18 (3171):
  • [33] Copper-Catalyzed Dehydrogenative Cross-Coupling of Benzothiazoles with Thiazoles and Polyfluoroarene
    Fan, Shilu
    Chen, Zhao
    Zhang, Xingang
    ORGANIC LETTERS, 2012, 14 (18) : 4950 - 4953
  • [34] Copper-catalyzed cross-coupling of alkylsamarium reagents with alkyl halides
    Berkowitz, WF
    Wu, YZ
    TETRAHEDRON LETTERS, 1997, 38 (18) : 3171 - 3174
  • [35] Iron catalyzed cross-coupling with TMEDA
    Sears, Jeffrey
    Neidig, Michael
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [36] Recent Advances in Copper-Catalyzed Carbon Chalcogenides Cross-Coupling Reactions
    Roy, Totan
    Mahata, Atanu
    Kundu, Debasish
    CURRENT ORGANIC SYNTHESIS, 2023, 20 (03) : 267 - 277
  • [37] The copper-catalyzed cross-coupling reactions of aryl diazonium salts and isocyanides
    Y. Li
    J. Cao
    Q. Zhu
    X. Zhang
    G. Shi
    Russian Journal of General Chemistry, 2016, 86 : 668 - 671
  • [38] Photoinduced Copper-Catalyzed Asymmetric C-O Cross-Coupling
    Chen, Jun
    Liang, Yu-Jie
    Wang, Peng-Zi
    Li, Guo-Qing
    Zhang, Bin
    Qian, Hao
    Huan, Xiao-Die
    Guan, Wei
    Xiao, Wen-Jing
    Chen, Jia-Rong
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2021, 143 (33) : 13382 - 13392
  • [39] Copper-catalyzed arene C-H bond cross-coupling
    Do, Hien-Quang
    Daugulis, Olafs
    CHEMICAL COMMUNICATIONS, 2009, (42) : 6433 - 6435
  • [40] Ascorbate mediated copper catalyzed reductive cross-coupling of disulfides with aryl iodides
    Martinek, Marek
    Korf, Michal
    Srogl, Jiri
    CHEMICAL COMMUNICATIONS, 2010, 46 (24) : 4387 - 4389
12345