Application of 2-D graphical representation of DNA sequence

被引:49
|
作者
Liao, B [1 ]
Tan, MS
Ding, KQ
机构
[1] Hunan Univ, Sch Comp & Commun, Dept Comp Sci, Changsha 410082, Hunan, Peoples R China
[2] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
[3] Chongqing Univ, Chongqing 404000, Wanzhou, Peoples R China
关键词
D O I
10.1016/j.cplett.2005.08.079
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Recently, we proposed a 2-D graphical representation of DNA sequence [Bo Liao, A 2-D graphical representation of DNA sequence, Chem. Phys. Lett. 401 (2005) 196-199]. Based on this representation, we consider properties of mutations and compute the similarities among 11 mitochondrial sequences belonging to different species. The elements of the similarity matrix are used to construct phylogenic tree. Unlike most existing phylogeny construction methods, the proposed method does not require multiple alignment. (c) 2005 Elsevier B.V. All rights reserved.
引用
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页码:296 / 300
页数:5
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