Radical cyclizations of 1,4-dihydropyridines. Synthesis of chiral fused nitrogen heterocycles. Synthesis of lupinine and epilupinine.

被引：36

作者：

Mangeney, P ^{[1
]}

Hamon, L ^{[1
]}

Raussou, S ^{[1
]}

Urbain, N ^{[1
]}

Alexakis, A ^{[1
]}

机构：

[1] Univ Paris 06, CNRS, Lab Chim Organoelements, F-75252 Paris 05, France

来源：

TETRAHEDRON | 1998年 / 54卷 / 35期

关键词：

D O I：

10.1016/S0040-4020(98)00490-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Radical cyclizations of 1-(4-iodoalkanoyl)-3-formyl-4-methyl-1,4-dihydropyridines are described and discussed. A regio and diasteroselective reaction is obtained under ultrasonic conditions. An application to the synthesis of lupinine and epilupinine is shown. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：10349 / 10362

页数：14

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