Radical cyclizations of 1,4-dihydropyridines. Synthesis of chiral fused nitrogen heterocycles. Synthesis of lupinine and epilupinine.

被引：36
|
作者：
Mangeney, P [1 ]
Hamon, L [1 ]
Raussou, S [1 ]
Urbain, N [1 ]
Alexakis, A [1 ]
机构：
[1] Univ Paris 06, CNRS, Lab Chim Organoelements, F-75252 Paris 05, France
来源：
TETRAHEDRON | 1998年 / 54卷 / 35期
关键词：
D O I：
10.1016/S0040-4020(98)00490-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Radical cyclizations of 1-(4-iodoalkanoyl)-3-formyl-4-methyl-1,4-dihydropyridines are described and discussed. A regio and diasteroselective reaction is obtained under ultrasonic conditions. An application to the synthesis of lupinine and epilupinine is shown. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：10349 / 10362
页数：14
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