Syntheses, Spectral and Antifungal Studies of Some Metal Complexes Derived from a Macrocyclic Ligand

A new macrocyclic ligand 1-[5-(1-{2-[1-(5-acetyl-2,4-dihydroxyphenyl)-ethylideneamino]-phenylimino)-ethyl)-2,4 dihydroxy-phenyl]-ethanone was prepared by condensation of ethanolic solutions of 4,6-diacetyl resorcinol and o-phenylenediamine. The ligand was characterized by H-1- & C-13-NMR, IR, Mass spectral data and analytical data. Metal complexes with this new macrocyclic ligand have been prepared with VO(IV), Mn(II), Fe(II), Co(II), Ni(II), Cd(II) and Cu(II). The metal chelates were characterized by elemental analyses, Molar conductance measurements, Magnetic susceptibility measurements, IR, UV Vis spectra. The ligand and the complexes were screened for anti fungal activity against Aspergillus terreus. The order of inhibition has been found to be Cu(II) >Cd(II) >Co (II)>VO (IV)>Fe (II)>Ni (II)>Mn (II)>Ligand.