Syntheses,Spectral Studies and Bioanalyses of Some Triorganotin(IV) Complexes of Cephlaxine

被引：0
|
作者：
Wajid Rehman
Bakhtiar Muhammad
Farman Ali
Sardar Atif
机构：
[1] Department of Chemistry Hazara University Mansehra
[2] Pakistan
来源：
Chinese Journal of Structural Chemistry | 2008年 / 07期
关键词：
cephlaxine; spectra; triorganotin; activity; bacteria;
D O I：
10.14102/j.cnki.0254-5861.2008.07.013
中图分类号：
O621.3 [有机合成化学];
学科分类号：
070303 ; 081704 ;
摘要：
Five novel triorganotin(IV) complexes have been synthesized by refluxing tri-methyl, triethyl, tributyl, triphenyl and tribenzyltin chloride with Cephlaxine. These compounds were characterized by spectroscopic (IR, 1H, 13C, 119Sn NMR) techniques and elemental analysis. The results obtained through these techniques are in full agreement with the proposed 1:1 stoichiometry. The synthesized compounds were than tested against various microorganisms and fungi. The results of new products obtained showed that the triphenyltin(IV) complex displayed promising activity against all types of bacteria and fungi used while all other compounds showed significant antibacterial and antifungal activity.
引用
收藏
页码：846 / 852
页数：7
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