Optimization of synthetically novel agonists of the putative cannabinoid receptor, GPR55, using an activated state model

被引:0
|
作者
Lingerfelt, Mary [1 ]
Alfakhori, Lara [2 ]
Hurst, Dow [1 ]
Zhao, Pingwei [3 ]
Croatt, Mitch [2 ]
Abood, Mary [3 ]
Reggio, Patricia [2 ]
机构
[1] Univ North Carolina Greensboro, Chem & Biochem, Pleasant Garden, NC USA
[2] Univ North Carolina Greensboro, Chem & Biochem, Greensboro, NC USA
[3] Temple Univ, Anat & Cell Biol, Philadelphia, PA 19122 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
61
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Atypical Responsiveness of the Orphan Receptor GPR55 to Cannabinoid Ligands
    Kapur, Ankur
    Zhao, Pingwei
    Sharir, Haleli
    Bai, Yushi
    Caron, Marc G.
    Barak, Larry S.
    Abood, Mary E.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (43) : 29817 - 29827
  • [22] The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain
    Staton, Penny C.
    Hatcher, Jon P.
    Walker, Deborah J.
    Morrison, Alastair D.
    Shapland, Ellen M.
    Hughes, Jane P.
    Chong, Elizabeth
    Mander, Palwinder K.
    Green, Paula J.
    Billinton, Andy
    Fulleylove, Michael
    Lancaster, Hilary C.
    Smith, Jason C.
    Bailey, Leigh T.
    Wise, Alan
    Brown, Andrew J.
    Richardson, Jill C.
    Chessell, Iain P.
    PAIN, 2008, 139 (01) : 225 - 236
  • [23] GPR55: A novel cannabinoid receptor involved in the regulation of osteoclast function and bone mass
    Whyte, L.
    Ryberg, E.
    Sims, N. A.
    Ridge, S.
    Mackie, K.
    Greasley, P.
    Ross, R. A.
    Rogers, M. J.
    BONE, 2009, 44 : S138 - S138
  • [24] Exploration and maximization of GPR55 antagonists using synthetically diversified ligands
    Lingerfelt, Mary A.
    Sharir, Haleli
    Hurst, Dow P.
    Abood, Mary H.
    Reggio, Patricia H.
    Croatt, Mitch P.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [25] GPR55 as a new cannabinoid receptor: Still a long way to prove it
    Petitet, F
    Donlan, M
    Michel, A
    CHEMICAL BIOLOGY & DRUG DESIGN, 2006, 67 (03) : 252 - 253
  • [26] Activation of the Novel Cannabinoid Receptor, GPR55, Mediates the Antiproliferative Effects of Anandamide on Cholangiocarcinoma Growth
    Ramirez, Jonathan
    Frampton, Gabriel A.
    Brennan, Andrew
    Huang, Li
    Mohamad, Akimuddin
    DeMorrow, Sharon
    GASTROENTEROLOGY, 2010, 138 (05) : S792 - S792
  • [27] The novel cannabinoid receptor GPR55 binds atypical cannabinoids but does not mediate their vasodilatory effects
    Johns, Douglas G.
    Behm, David J.
    Ao, Zhaohui
    Walker, Debbie
    Parsons, Michael
    Senadhi, Shobha
    T Goserud, Matthew
    Daniels, Dion A.
    Riddick, Michelle
    Staton, Penelope C.
    Green, Paula
    Bao, Welke
    Aiyar, Nambi
    Yue, Tian-Li
    Brown, Andrew J.
    Morrison, Alastair D.
    Douglas, Stephen A.
    HYPERTENSION, 2006, 48 (04) : E86 - E86
  • [28] Identification and characterisation of putative modulator ligands at the orphan receptor GPR55
    Haslam, C.
    Kitchen, V.
    Brough, S.
    Kassim, M.
    Daniels, D.
    Brown, A.
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2008, 22 : 70 - 70
  • [29] A putative lysophosphatidylinositol receptor GPR55 modulates hippocampal synaptic plasticity
    Hurst, Katrina
    Badgley, Corinne
    Ellsworth, Tanner
    Bell, Spencer
    Friend, Lindsey
    Prince, Brad
    Welch, Jacob
    Cowan, Zack
    Williamson, Ryan
    Lyon, Chris
    Anderson, Brandon
    Poole, Brian
    Christensen, Michael
    McNeil, Michael
    Call, Jarrod
    Edwards, Jeffrey G.
    HIPPOCAMPUS, 2017, 27 (09) : 985 - 998
  • [30] Systematic synthesis of novel phosphoglycolipid analogues as potential agonists of GPR55
    Abe, Junpei
    Guy, Adam T.
    Ding, Feiqing
    Greimel, Peter
    Hirabayashi, Yoshio
    Kamiguchi, Hiroyuki
    Ito, Yukishige
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2020, 18 (41) : 8467 - 8473