Straightforward synthesis of ynones by reaction of dimethylalkynylaluminum reagents with acid chlorides

被引：66
|
作者：
Wang, BM
Bonin, M
Micouin, L
机构：
[1] CNRS, UMR 8636, Chim Therapeut Lab, F-75270 Paris, France
[2] Univ Paris 05, Fac Sci Pharmaceut & Biol, F-75270 Paris, France
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 15期
关键词：
D O I：
10.1021/jo050760y
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Alkynyldimethylaluminum reagents react with various aromatic and aliphatic acid chlorides in a fast and efficient way. This reaction provides a simple entry to numerous ynones, using readily available, inexpensive, and nontoxic metalating agent, and does not require any transition metal as a catalyst.
引用
收藏
页码：6126 / 6128
页数：3
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