Intrinsic DNA Replication Stress Confers Sensitivity to ATR inhibitor in Lung Adenocarcinoma Cell

被引:0
|
作者
Kurashima, Kiminori [1 ]
Kohno, Takashi [2 ]
Shiotani, Bunsyo [1 ]
机构
[1] Natl Canc Ctr, Res Inst, Div Cell Signaling, Tokyo, Japan
[2] Natl Canc Ctr, Res Inst, Div Genome Biol, Tokyo, Japan
来源
CANCER SCIENCE | 2018年 / 109卷
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
J-1008
引用
收藏
页码:271 / 271
页数:1
相关论文
共 50 条
  • [31] An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress
    Taichi Igarashi
    Marianne Mazevet
    Takaaki Yasuhara
    Kimiyoshi Yano
    Akifumi Mochizuki
    Makoto Nishino
    Tatsuya Yoshida
    Yukihiro Yoshida
    Nobuhiko Takamatsu
    Akihide Yoshimi
    Kouya Shiraishi
    Hidehito Horinouchi
    Takashi Kohno
    Ryuji Hamamoto
    Jun Adachi
    Lee Zou
    Bunsyo Shiotani
    Nature Communications, 14 (1)
  • [32] Loss of NEIL3 DNA glycosylase markedly increases replication associated double strand breaks and enhances sensitivity to ATR inhibitor in glioblastoma cells
    Klattenhoff, Alex W.
    Thakur, Megha
    Chu, Christopher S.
    Ray, Debolina
    Habib, Samy L.
    Kidane, Dawit
    ONCOTARGET, 2017, 8 (68) : 112942 - 112958
  • [33] Hydroquinone reduces DNA replication tolerance to stress and increases chemotherapy sensitivity in oral squamous cell carcinoma
    Huang, Zhibin
    Hong, Xiaobin
    MATERIALS EXPRESS, 2023, 13 (05) : 779 - 784
  • [34] Acute sensitivity of DNA replication to reduction in dNTP pools following Mec1ATR inactivation
    Earp, Caroline
    Rowbotham, Samuel
    Marjavaara, Lisette
    Chabes, Andrei
    Cha, Rita S.
    YEAST, 2015, 32 : S56 - S56
  • [35] Use of ATR inhibitor in combination with topoisomerase I inhibitor kills cancer cells by disabling DNA replication initiation and fork elongation
    Josse, R.
    Martin, S. E.
    Guha, R.
    Ormanoglu, P.
    Pfister, T.
    Morris, J.
    Doroshow, J.
    Pommier, Y.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : 83 - 83
  • [36] DNA methylation profiling in lung adenocarcinoma cell lines
    Heller, Gerwin
    Ziegler, Barbara
    Gsur, Andrea
    Zielinski, Christoph
    Zoechbauer-Mueller, Sabine
    CANCER RESEARCH, 2009, 69
  • [37] Effect of Furin inhibitor on lung adenocarcinoma cell growth and metastasis
    Yong-Chao Ma
    Wen-Juan Fan
    Shu-Mei Rao
    Li Gao
    Zhan-Yu Bei
    Song-Tao Xu
    Cancer Cell International, 14
  • [38] Effect of Furin inhibitor on lung adenocarcinoma cell growth and metastasis
    Ma, Yong-Chao
    Fan, Wen-Juan
    Rao, Shu-Mei
    Gao, Li
    Bei, Zhan-Yu
    Xu, Song-Tao
    CANCER CELL INTERNATIONAL, 2014, 14
  • [39] An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced replication stress supporting clonal expansion.
    Shiotani, Bunsyo
    CANCER SCIENCE, 2024, 115 : 495 - 495
  • [40] Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress
    Vassin, Vitaly M.
    Anantha, Rachel William
    Sokolova, Elena
    Kanner, Shlomo
    Borowiec, James A.
    JOURNAL OF CELL SCIENCE, 2009, 122 (22) : 4070 - 4080